Automated Organization Profile

State Key Laboratory of Stem Cell and Reproductive Biology Institute of Stem Cell and Regeneration, Chinese Academy of Sciences Institute of Zoology, Chinese Academy of Sciences

Current S-Index

0.5

Sum of Dataset Indices for all datasets

Average Dataset Index per Dataset

0.5

Average Dataset Index per dataset

Total Datasets

1

Total datasets in this organization

Average FAIR Score

15.4%

Average FAIR Score per dataset

Total Citations

1

Total citations to the organization's datasets

Total Mentions

0

Total mentions of the organization's datasets

S-Index Interpretation

S-Index Over Time

Cumulative Citations Over Time

Cumulative Mentions Over Time

Datasets

BNIP3-dependent mitophagy safeguards ESC genomic integrity via preventing oxidative stress-induced DNA damage and protecting homologous recombination (Version: V1)

We propagated Bnip3+/+, vector-bnip3-/-, ∆LIR-bnip3-/-, and WT-bnip3-/- ESCs routinely for 30 passages either under normal conditions or with NAC or H2O2 treatment. Then we performed whole genomic sequencing on each cell line at either initial passage or after propagation for 30 passages. Compared to Bnip3+/+ ESCs, the bnip3-/- ESC genome accumulated more mutations during long-term propagation. The details of data are available from the corresponding author on reasonable request.

Authors

  • Tongbiao, Zhao
1 Citation0 Mentions15% FAIR0.5 Dataset Index
10.57760/sciencedb.02743September 2022