Automated Organization Profile

Department of Biochemistry, Faculty of Medical Science, Naresuan University, Phitsanulok, Thailand

Current S-Index

3.2

Sum of Dataset Indices for all datasets

Average Dataset Index per Dataset

1.6

Average Dataset Index per dataset

Total Datasets

2

Total datasets in this organization

Average FAIR Score

73.1%

Average FAIR Score per dataset

Total Citations

0

Total citations to the organization's datasets

Total Mentions

0

Total mentions of the organization's datasets

S-Index Interpretation

S-Index Over Time

Cumulative Citations Over Time

Cumulative Mentions Over Time

Datasets

Combination of ethyl acetate fraction from Calotropis gigantea stem bark and sorafenib induced apoptosis in HepG2 cells

S1 Fig. The high-pressure liquid chromatography-electrospray ionisation-mass spectroscopic (HPLC-ESI-MS) chromatogram of C. gigantea stem bark extracts (CGEtOAc) in negative mode.S2 Fig. The IC50 curves for (A) CGEtOAc and (B) sorafenib in HepG2 cells, and (C) CGEtOAc in IMR-90 cells for 24 h of incubation.S3 Fig. The combination index (CI) vs. fraction affected (Fa) graph for CGEtOAc in combination with sorafenib after 24 h of incubation.S4 Fig. The migration rate of HepG2 cells treated with CGEtOAc at 400 µg/mL and sorafenib at 4 µM, both singly and in combination, was evaluated using a wound healing assay after 0-72 h of incubation and compared to the vehicle group. S5 Raw images displaying the gating strategies used in flow cytometry of annexin V and propidium iodide (PI) staining in HepG2 cells after 24 h of incubation, with a combination of 400 µg/mL CGEtOAc and 4 µM sorafenib.S6 Raw images of the original uncropped and unadjusted western blot images for HepG2 cells treated with a combination of 400 µg/mL CGEtOAc and 4 µM sorafenib for a 24-h incubation period.

Authors

  • Chaisupasakul, Pattaraporn ;
  • Pekthong, Dumrongsak ;
  • Wangteeraprasert, Apirath ;
  • KAEWKONG, WORASAK ;
  • Somran, Julintorn ;
  • Kaewpaeng, Naphat ;
  • Parhira, Supawadee ;
  • SRISAWANG, PIYARAT
0 Citations0 Mentions73% FAIR1.6 Dataset Index
10.5281/zenodo.10799946March 2024

Combination of ethyl acetate fraction from Calotropis gigantea stem bark and sorafenib induced apoptosis in HepG2 cells

S1 Fig. The high-pressure liquid chromatography-electrospray ionisation-mass spectroscopic (HPLC-ESI-MS) chromatogram of C. gigantea stem bark extracts (CGEtOAc) in negative mode.S2 Fig. The IC50 curves for (A) CGEtOAc and (B) sorafenib in HepG2 cells, and (C) CGEtOAc in IMR-90 cells for 24 h of incubation.S3 Fig. The combination index (CI) vs. fraction affected (Fa) graph for CGEtOAc in combination with sorafenib after 24 h of incubation.S4 Fig. The migration rate of HepG2 cells treated with CGEtOAc at 400 µg/mL and sorafenib at 4 µM, both singly and in combination, was evaluated using a wound healing assay after 0-72 h of incubation and compared to the vehicle group. S5 Raw images displaying the gating strategies used in flow cytometry of annexin V and propidium iodide (PI) staining in HepG2 cells after 24 h of incubation, with a combination of 400 µg/mL CGEtOAc and 4 µM sorafenib.S6 Raw images of the original uncropped and unadjusted western blot images for HepG2 cells treated with a combination of 400 µg/mL CGEtOAc and 4 µM sorafenib for a 24-h incubation period.

Authors

  • Chaisupasakul, Pattaraporn ;
  • Pekthong, Dumrongsak ;
  • Wangteeraprasert, Apirath ;
  • KAEWKONG, WORASAK ;
  • Somran, Julintorn ;
  • Kaewpaeng, Naphat ;
  • Parhira, Supawadee ;
  • SRISAWANG, PIYARAT
0 Citations0 Mentions73% FAIR1.6 Dataset Index
10.5281/zenodo.10799945March 2024