The importance and impact of feminist mobilization across borders is well documented, but the impact of autonomy as an aspect of such organizing has not been explored in the transnational context. We argue that to understand the impact of transnational feminist mobilization, at least two distinct types of feminist mobilization require further conceptual development and empirical exploration in the transnational context, namely, autonomous as contrasted with multilateral mobilization. We offer a conceptual framework for distinguishing and studying these two forms. Further, using a mixed-methods study design, we empirically distinguish domestic and transnational dimensions of feminist activism and illuminate the impact of both multilateral feminist organizing and autonomous feminist organizing in the transnational space. Our analysis reveals that domestic and transnational organizing are distinct but related phenomena. We also find that in online organizing spaces, autonomous feminist campaigns amplify the messaging of geographically dispersed grassroots and individual activists more than multilateral ones. It further suggests that autonomous movements may offer more potential for representing marginalized groups of women, though this potential may not always be realized. The paper offers new concepts and empirical insights for the study of transnational feminism, thereby enabling a new research agenda. Further, this research contributes to the study of the ways that Transnational Social Movements can enrich global civil society and deepen global democracy.