Automated Organization Profile

Oregon Stem Cell Center

Current S-Index

0.7

Sum of Dataset Indices for all datasets

Average Dataset Index per Dataset

0.7

Average Dataset Index per dataset

Total Datasets

1

Total datasets in this organization

Average FAIR Score

57.7%

Average FAIR Score per dataset

Total Citations

1

Total citations to the organization's datasets

Total Mentions

0

Total mentions of the organization's datasets

S-Index Interpretation

S-Index Over Time

Cumulative Citations Over Time

Cumulative Mentions Over Time

Datasets

Identification of genes regulated by Rcor1 in CD71+, TER119- erythroid progenitors using mRNA-seq analysis (Version: 1.0)

Transcription cofactor Rcor1 has been linked biochemically both to neurogenesis and hematopoiesis. Here we studied the function of Rcor1 in vivo and showed it is essential to erythropoeisis during embryonic development. Rcor1 mutant proerythroblasts, unlike normal cells, can form myeloid colonies in vitro. To investigate the underlying molecular mechanisms for block of erythropoiesis and increased myeloid potential, we used RNA-seq to reveal the differentially expressed genes from erythroid progenitors due to depletion of Rcor1.

Authors

  • Yao, Huilan ;
  • Goldman, Devorah C. ;
  • Nechiporuk, Tamilla ;
  • Kawane, Sunita ;
  • McWeeney, Shannon K. ;
  • Tyner, Jeffrey W. ;
  • Fan, Guang ;
  • Kerenyi, Marc A. ;
  • Orkin, Stuart H. ;
  • Fleming, William H. ;
  • Mandel, Gail
1 Citation0 Mentions58% FAIR0.7 Dataset Index
10.7910/dvn/rgpbwn2020