Automated Author ProfileGiroldo, Lilian
Giroldo, Lilian
Current S-Index
Sum of Dataset Indices for all datasets
Average Dataset Index per Dataset
Average Dataset Index per dataset
Total Datasets
Total datasets for this author
Average FAIR Score
Average FAIR Score per dataset
Total Citations
Total citations to the author's datasets
Total Mentions
Total mentions of the author's datasets
S-Index Interpretation
The S-Index (Sharing Index) is a comprehensive metric that represents the cumulative impact of all your datasets. It is calculated as the sum of Dataset Index scores across all your claimed datasets.
What it means:
- A higher S-index indicates greater overall impact of your datasets relative to typical datasets in their fields of research
- The S-Index grows as you add more datasets or as existing datasets gain more citations and mentions
- It provides a single number to track your research data impact over time
Current S-Index: 1.4 (sum of 3 datasets Dataset Index scores)
More information here.
S-Index Over Time
Cumulative Citations Over Time
Cumulative Mentions Over Time
Datasets
This study describes a single step, high yield and purity, ecofriendly and scalable procedure to prepare a selenium derivative (diethyl selenodiglycolate). Diethyl selenodiglycolate rapidly reduces hypochlorous acid (HOCl, second-order rate constant of 7 × 107 M−1 s−1) to generate its corresponding selenoxide. In activated HL-60 cells, diethyl selenodiglycolate selectively reacted with HOCl (half maximal inhibitory concentration (IC50) = 23.07 µM) but not with superoxide anion radical or hydrogen peroxide without any cytotoxicity. These results show that this synthetically simple selenide reacts in a very efficient and specific way with the harmful pro-oxidant HOCl being a promising compound to be applied in oxidative inflammatory-related conditions.
Authors
- Pinatto-Botelho, Marcos F. ;
- Railmara P. Da Silva ;
- Archilha, Marcos V. L. R. ;
- Giroldo, Lilian ;
- Kuznetsov, Aleksey E. ;
- Meotti, Flávia C. ;
- Santos, Alcindo A. Dos
This study describes a single step, high yield and purity, ecofriendly and scalable procedure to prepare a selenium derivative (diethyl selenodiglycolate). Diethyl selenodiglycolate rapidly reduces hypochlorous acid (HOCl, second-order rate constant of 7 × 107 M−1 s−1) to generate its corresponding selenoxide. In activated HL-60 cells, diethyl selenodiglycolate selectively reacted with HOCl (half maximal inhibitory concentration (IC50) = 23.07 µM) but not with superoxide anion radical or hydrogen peroxide without any cytotoxicity. These results show that this synthetically simple selenide reacts in a very efficient and specific way with the harmful pro-oxidant HOCl being a promising compound to be applied in oxidative inflammatory-related conditions.
Authors
- Pinatto-Botelho, Marcos F. ;
- Railmara P. Da Silva ;
- Archilha, Marcos V. L. R. ;
- Giroldo, Lilian ;
- Kuznetsov, Aleksey E. ;
- Meotti, Flávia C. ;
- Santos, Alcindo A. Dos
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Authors
- Soares-Paulino, Antônio A. ;
- Giroldo, Lilian ;
- Celante, Gizele ;
- Oliveira, Elisabete ;
- Santos, Sérgio M. ;
- Mendes, Ricardo F. ;
- Paz, Filipe A. Almeida ;
- Fioroto, Alexandre M. ;
- Oliveria, Pedro V. ;
- Serrano, Silvia H.P. ;
- Lodeiro, Carlos ;
- Dos Santos, Alcindo A.