Automated Author Profile

Tovilla-Zárate, C.A.

Current S-Index

0.5

Sum of Dataset Indices for all datasets

Average Dataset Index per Dataset

0.2

Average Dataset Index per dataset

Total Datasets

2

Total datasets for this author

Average FAIR Score

13.5%

Average FAIR Score per dataset

Total Citations

0

Total citations to the author's datasets

Total Mentions

0

Total mentions of the author's datasets

S-Index Interpretation

S-Index Over Time

Cumulative Citations Over Time

Cumulative Mentions Over Time

Datasets

Supplementary Material for: Association between Polymorphisms of the DRD2 and ANKK1 Genes and Suicide Attempt: A Preliminary Case-Control Study in a Mexican Population

Background: The aim of this study was to analyze the possible association of polymorphic variants of the DRD2 and ANKK1 genes with suicide attempt in a Mexican population. Methods: We conducted a case-control study in 289 subjects (166 suicide attempters and 123 healthy controls). We genotyped 2 polymorphisms of DRD2 (rs6275 and rs1799978) and 1 polymorphism of ANKK1 (rs1800497); then we analyzed the association between suicide attempt and these polymorphisms through genotypes, alleles, and inheritance models. Results: Individuals who carried the TT genotype of the rs1800497 showed a 3-fold risk of attempting suicide (OR = 3.01; 95% CI 1.56–5.81, p = 0.001) when evaluated through the recessive model. In an analysis stratified by gender, this risk factor remained present among females (OR = 2.81; 95% CI 1.37–5.75) as well as males (OR = 3.3; 95% CI 1.01–10.77). Conclusion: Our results suggest that the rs1800497 variant of the ANKK1 gene could increase the risk of suicide attempt in a Mexican population. However, further studies using larger samples are necessary to obtain more conclusive results.

Authors

  • Genis-Mendoza, A.D. ;
  • López-Narvaez, M.L. ;
  • Tovilla-Zárate, C.A. ;
  • Sarmiento, E. ;
  • Chavez, A. ;
  • Martinez-Magaña, J.J. ;
  • González-Castro, T.B. ;
  • Hernández-Díaz, Y. ;
  • Juárez-Rojop, I.E. ;
  • Ávila-Fernández Á. ;
  • Nicolini, H.
0 Citations0 Mentions13% FAIR0.3 Dataset Index
10.6084/m9.figshare.6729347January 2018

Supplementary Material for: Association between Polymorphisms of the DRD2 and ANKK1 Genes and Suicide Attempt: A Preliminary Case-Control Study in a Mexican Population

Background: The aim of this study was to analyze the possible association of polymorphic variants of the DRD2 and ANKK1 genes with suicide attempt in a Mexican population. Methods: We conducted a case-control study in 289 subjects (166 suicide attempters and 123 healthy controls). We genotyped 2 polymorphisms of DRD2 (rs6275 and rs1799978) and 1 polymorphism of ANKK1 (rs1800497); then we analyzed the association between suicide attempt and these polymorphisms through genotypes, alleles, and inheritance models. Results: Individuals who carried the TT genotype of the rs1800497 showed a 3-fold risk of attempting suicide (OR = 3.01; 95% CI 1.56–5.81, p = 0.001) when evaluated through the recessive model. In an analysis stratified by gender, this risk factor remained present among females (OR = 2.81; 95% CI 1.37–5.75) as well as males (OR = 3.3; 95% CI 1.01–10.77). Conclusion: Our results suggest that the rs1800497 variant of the ANKK1 gene could increase the risk of suicide attempt in a Mexican population. However, further studies using larger samples are necessary to obtain more conclusive results.

Authors

  • Genis-Mendoza, A.D. ;
  • López-Narvaez, M.L. ;
  • Tovilla-Zárate, C.A. ;
  • Sarmiento, E. ;
  • Chavez, A. ;
  • Martinez-Magaña, J.J. ;
  • González-Castro, T.B. ;
  • Hernández-Díaz, Y. ;
  • Juárez-Rojop, I.E. ;
  • Ávila-Fernández Á. ;
  • Nicolini, H.
0 Citations0 Mentions13% FAIR0.1 Dataset Index
10.6084/m9.figshare.6729347.v1January 2018