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Kurth, Florian

Current S-Index

7.1

Sum of Dataset Indices for all datasets

Average Dataset Index per Dataset

1.2

Average Dataset Index per dataset

Total Datasets

6

Total datasets for this author

Average FAIR Score

73.1%

Average FAIR Score per dataset

Total Citations

14

Total citations to the author's datasets

Total Mentions

0

Total mentions of the author's datasets

S-Index Interpretation

S-Index Over Time

Cumulative Citations Over Time

Cumulative Mentions Over Time

Datasets

Messingschlager_et_al_6_months_follow-up_samples_n15_scRNA-seq_Nasopharynx_epithelial_cells.rds

This dataset comprises single-cell RNA-Seq data of nasopharyngeal samples of adults 6-month post SARS-CoV-2 infection (n=15) with and without 
remaining respiratory symptoms (n=6 and 9, respectively).

An in-depth description is presented in the manuscript "DNA Methylation 
Changes During Acute COVID-19 are Associated with Long-Term 
Transcriptional Dysregulation in Patients’ Airway Epithelial Cells".

Authors

  • Trump, Saskia ;
  • Messingschlager, Marey ;
  • Mackowiak, Sebastian D. ;
  • Völker, Maria Theresa ;
  • Bieg, Matthias ;
  • Loske, Jennifer ;
  • Chua, Robert Lorenz ;
  • Liebig, Johannes ;
  • Lukassen, Sören ;
  • Thürmann, Loreen ;
  • Seegebarth, Anke ;
  • Twardziok, Sven ;
  • Doncevic, Daria ;
  • Herrmann, Carl ;
  • Lorenz, Stephan ;
  • Klages, Sven ;
  • Steinbeis, Fridolin ;
  • Witzenrath, Martin ;
  • Kurth, Florian ;
  • Conrad, Christian ;
  • Sander, Leif-Erik ;
  • Ishaque, Naveed ;
  • Eils, Roland ;
  • Lehmann, Irina ;
  • Laudi, Sven
0 Citations0 Mentions85% FAIR0.1 Dataset Index
10.6084/m9.figshare.284859142025

Messingschlager_et_al_6_months_follow-up_samples_n15_scRNA-seq_Nasopharynx_epithelial_cells.rds

This dataset comprises single-cell RNA-Seq data of nasopharyngeal samples of adults 6-month post SARS-CoV-2 infection (n=15) with and without 
remaining respiratory symptoms (n=6 and 9, respectively).

An in-depth description is presented in the manuscript "DNA Methylation 
Changes During Acute COVID-19 are Associated with Long-Term 
Transcriptional Dysregulation in Patients’ Airway Epithelial Cells".

Authors

  • Trump, Saskia ;
  • Messingschlager, Marey ;
  • Mackowiak, Sebastian D. ;
  • Völker, Maria Theresa ;
  • Bieg, Matthias ;
  • Loske, Jennifer ;
  • Chua, Robert Lorenz ;
  • Liebig, Johannes ;
  • Lukassen, Sören ;
  • Thürmann, Loreen ;
  • Seegebarth, Anke ;
  • Twardziok, Sven ;
  • Doncevic, Daria ;
  • Herrmann, Carl ;
  • Lorenz, Stephan ;
  • Klages, Sven ;
  • Steinbeis, Fridolin ;
  • Witzenrath, Martin ;
  • Kurth, Florian ;
  • Conrad, Christian ;
  • Sander, Leif-Erik ;
  • Ishaque, Naveed ;
  • Eils, Roland ;
  • Lehmann, Irina ;
  • Laudi, Sven
0 Citations0 Mentions85% FAIR0.1 Dataset Index
10.6084/m9.figshare.28485914.v12025

Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung

Source data for the manuscript "Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung"

Authors

  • Dörner, Patrick ;
  • Anandakumar, Harithaa ;
  • Röwekamp, Ivo ;
  • Fiocca Vernengo, Facundo ;
  • Millet Pascual-Leone, Belén ;
  • Krzanowski, Marta ;
  • Sellmaier, Josua ;
  • Brüning, Ulrike ;
  • Fritsche-Guenther, Raphaela ;
  • Pfannkuch, Lennart ;
  • Kurth, Florian ;
  • Milek, Miha ;
  • Igbokwe, Vanessa ;
  • Löber, Ulrike ;
  • Gutbier, Birgitt ;
  • Holstein, Markus ;
  • Heinz, Gitta ;
  • Mashreghi, Mir-Fazin ;
  • Schulte, Leon ;
  • Klatt, Ann-Brit ;
  • Caesar, Sandra ;
  • Wienhold, Sandra-Maria ;
  • Offermanns, Stefan ;
  • Mack, Matthias ;
  • Witzenrath, Martin ;
  • Jordan, Stefan ;
  • Beule, Dieter ;
  • Kirwan, Jennifer A. ;
  • Forslund, Sofia ;
  • Wilck, Nicola ;
  • Bartolomaeus, Hendrik ;
  • Heimesaat, Markus ;
  • Opitz, Bastian
1 Citation0 Mentions15% FAIR0.7 Dataset Index
10.6084/m9.figshare.252433332024

Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung

Source data for the manuscript "Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung"

Authors

  • Dörner, Patrick ;
  • Anandakumar, Harithaa ;
  • Röwekamp, Ivo ;
  • Fiocca Vernengo, Facundo ;
  • Millet Pascual-Leone, Belén ;
  • Krzanowski, Marta ;
  • Sellmaier, Josua ;
  • Brüning, Ulrike ;
  • Fritsche-Guenther, Raphaela ;
  • Pfannkuch, Lennart ;
  • Kurth, Florian ;
  • Milek, Miha ;
  • Igbokwe, Vanessa ;
  • Löber, Ulrike ;
  • Gutbier, Birgitt ;
  • Holstein, Markus ;
  • Heinz, Gitta ;
  • Mashreghi, Mir-Fazin ;
  • Schulte, Leon ;
  • Klatt, Ann-Brit ;
  • Caesar, Sandra ;
  • Wienhold, Sandra-Maria ;
  • Offermanns, Stefan ;
  • Mack, Matthias ;
  • Witzenrath, Martin ;
  • Jordan, Stefan ;
  • Beule, Dieter ;
  • Kirwan, Jennifer A. ;
  • Forslund, Sofia ;
  • Wilck, Nicola ;
  • Bartolomaeus, Hendrik ;
  • Heimesaat, Markus ;
  • Opitz, Bastian
1 Citation0 Mentions85% FAIR0.7 Dataset Index
10.6084/m9.figshare.25243333.v12024

COVID-19 severity correlates with airway epithelium-immune cell interactions identified by single-cell analysis

Single-cell RNA-Seq of airway samples of COVID-19 patients and healthy controls
This dataset comprises single-cell RNA-Seq data of nasopharyngeal, protected specimen brush, and bronchial lavage samples of 19 COVID-19 patients (eight moderate and eleven critical according to the WHO classification) and five healthy controls, for a total of 36 samples.
An in-depth description is presented in the manuscript "Cross-talk between the airway epithelium and activated immune cells defines severity in COVID-19" (https://www.medrxiv.org/content/10.1101/2020.04.29.20084327v1).
The data is uploaded as two .rds files of Seurat objects that can be imported into R. The _main file contains all samples from the nasopharynx, while the _loc file contains data from nasopharyngeal, protected specimen brush, and bronchial lavage samples of two patients.
A quantification of viral RNA reads (as CPM, in total over cells and background) is provided as .xlsx file. Please note that these values may differ from viral load estimates obtained from diagnostic procedures and may be less accurate.Raw count values (cellranger output) are provided in the file count_matrices_NBT.tar.

Authors

  • Chua, Robert Lorenz ;
  • Lukassen, Soeren ;
  • Trump, Saskia ;
  • Hennig, Bianca P. ;
  • Wendisch, Daniel ;
  • Pott, Fabian ;
  • Debnath, Olivia ;
  • Thürmann, Loreen ;
  • Kurth, Florian ;
  • Völker, Maria Theresa ;
  • Kazmierski, Julia ;
  • Timmermann, Bernd ;
  • Twardziok, Sven ;
  • Schneider, Stefan ;
  • Machleidt, Felix ;
  • Müller-Redetzky, Holger ;
  • Maier, Melanie ;
  • Krannich, Alexander ;
  • Schmidt, Sein ;
  • Balzer, Felix ;
  • Liebig, Johannes ;
  • Loske, Jennifer ;
  • Suttorp, Norbert ;
  • Eils, Jürgen ;
  • Ishaque, Naveed ;
  • Gerd Liebert, Uwe ;
  • von Kalle, Christof ;
  • Hocke, Andreas ;
  • Witzenrath, Martin ;
  • Goffinet, Christine ;
  • Drosten, Christian ;
  • Laudi, Sven ;
  • Lehmann, Irina ;
  • Conrad, Christian ;
  • Sander, Leif-Erik ;
  • Eils, Roland
12 Citations0 Mentions85% FAIR5.4 Dataset Index
10.6084/m9.figshare.124365172020

Hypertension delays viral clearance and exacerbates airway hyperinflammation in patients with COVID-19

This dataset comprises single-cell RNA-Seq data of nasopharyngeal samples of 32 COVID-19 patients and 16 healthy controls, for a total of 48 samples. 25 COVID-19 patients and 10 controls were diagnosed with hypertension and treated with either ACE inhibitors (ACEi) or angiotensin receptor blockers(ARB) (SARS-CoV-2-positive: 10 ACEi and 15 ARB; SARS-CoV-2-negative: 6 ACEi and 4 ARB).
An in-depth description is presented in the manuscript "Delayed viral clearance and exacerbated airway hyperinflammation in hypertensive COVID-19 patients" (https://www.medrxiv.org/content/10.1101/2020.09.22.20199471v1).

Authors

  • Trump, Saskia ;
  • Lukassen, Soeren ;
  • Anker, Markus S. ;
  • Chua, Robert Lorenz ;
  • Liebig, Johannes ;
  • Thürmann, Loreen ;
  • Max Corman, Victor ;
  • Binder, Marco ;
  • Loske, Jennifer ;
  • Klasa, Christina ;
  • Krieger, Teresa G. ;
  • Hennig, Bianca P ;
  • Messingschlager, Marey ;
  • Pott, Fabian ;
  • Kazmierski, Julia ;
  • O. Twardziok, Sven ;
  • Albrecht, Jan Philipp ;
  • Eils, Jürgen ;
  • Hadzibegovic, Sara ;
  • Lena, Alessia ;
  • Heidecker, Bettina ;
  • Bürgel, Thore ;
  • Steinfeldt, Jakob ;
  • Goffinet, Christine ;
  • Kurth, Florian ;
  • Witzenrath, Martin ;
  • Völker, Maria Theresa ;
  • Müller, Sarah Dorothea ;
  • Gerd Liebert, Uwe ;
  • Ishaque, Naveed ;
  • Kaderali, Lars ;
  • Sander, Leif-Erik ;
  • Drosten, Christian ;
  • Laudi, Sven ;
  • Eils, Roland ;
  • Conrad, Christian ;
  • Landmesser, Ulf ;
  • Lehmann, Irina
0 Citations0 Mentions85% FAIR0.3 Dataset Index
10.6084/m9.figshare.132002782020