Automated Author Profile

Tsygankov, Denis

Current S-Index

6.7

Sum of Dataset Indices for all datasets

Average Dataset Index per Dataset

1.7

Average Dataset Index per dataset

Total Datasets

4

Total datasets for this author

Average FAIR Score

65.4%

Average FAIR Score per dataset

Total Citations

4

Total citations to the author's datasets

Total Mentions

0

Total mentions of the author's datasets

S-Index Interpretation

S-Index Over Time

Cumulative Citations Over Time

Cumulative Mentions Over Time

Datasets

Simulated patterns of CCM tube formation

This set includes 100 images of endothelial formations simulated with a model that allows for generating a range of different multicellular patterns depending on two biomechanical characteristics: the stability of cell-cell contacts and the strength of cell-matrix adhesion (Chernaya O, Zhurikhina A, Hladyshau S, Pilcher W, Young KM, Ortner J, Andra V, Sulchek TA, Tsygankov D. 2018. Biomechanics of Endothelial Tubule Formation Differentially Modulated by Cerebral Cavernous Malformation Proteins. iScience 9:347-358.)

Authors

  • Tsygankov, Denis
0 Citations0 Mentions65% FAIR1.4 Dataset Index
10.17632/mbh97cgss32020

Simulated patterns of CCM tube formation

This set includes 100 images of endothelial formations simulated with a model that allows for generating a range of different multicellular patterns depending on two biomechanical characteristics: the stability of cell-cell contacts and the strength of cell-matrix adhesion (Chernaya O, Zhurikhina A, Hladyshau S, Pilcher W, Young KM, Ortner J, Andra V, Sulchek TA, Tsygankov D. 2018. Biomechanics of Endothelial Tubule Formation Differentially Modulated by Cerebral Cavernous Malformation Proteins. iScience 9:347-358.)

Authors

  • Tsygankov, Denis
2 Citations0 Mentions65% FAIR2.1 Dataset Index
10.17632/mbh97cgss3.12020

In-vitro CCM tube formation

This set includes segmented images of the control cell (wild-type HUVEC) and cells with knockdown (KD) of the three Cerebral Cavernous Malformation (CCM) proteins, CCM1 (or KRIT1), CCM2, and CCM3 (or PDCD10), which disrupts the integrity of multicellular mesh. In addition, the control and KD cells were treated with an inhibitor of Rho-associated protein kinase (ROCK), which was shown to be over-activated in CCM KD cultures (Chernaya O, Zhurikhina A, Hladyshau S, Pilcher W, Young KM, Ortner J, Andra V, Sulchek TA, Tsygankov D. 2018. Biomechanics of Endothelial Tubule Formation Differentially Modulated by Cerebral Cavernous Malformation Proteins. iScience 9:347-358.8)

Authors

  • Tsygankov, Denis
0 Citations0 Mentions65% FAIR1.6 Dataset Index
10.17632/77wmwpznx92020

In-vitro CCM tube formation

This set includes segmented images of the control cell (wild-type HUVEC) and cells with knockdown (KD) of the three Cerebral Cavernous Malformation (CCM) proteins, CCM1 (or KRIT1), CCM2, and CCM3 (or PDCD10), which disrupts the integrity of multicellular mesh. In addition, the control and KD cells were treated with an inhibitor of Rho-associated protein kinase (ROCK), which was shown to be over-activated in CCM KD cultures (Chernaya O, Zhurikhina A, Hladyshau S, Pilcher W, Young KM, Ortner J, Andra V, Sulchek TA, Tsygankov D. 2018. Biomechanics of Endothelial Tubule Formation Differentially Modulated by Cerebral Cavernous Malformation Proteins. iScience 9:347-358.8)

Authors

  • Tsygankov, Denis
2 Citations0 Mentions65% FAIR2.3 Dataset Index
10.17632/77wmwpznx9.12020