Automated Author ProfileMy, Ilaria
IRCCS Humanitas Research Hospital, via Manzoni 56,20089 Rozzano (Mi) - Italy AND Humanitas University, Department of Biomedical Sciences, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele – Milan, Italy
My, Ilaria
Current S-Index
Sum of Dataset Indices for all datasets
Average Dataset Index per Dataset
Average Dataset Index per dataset
Total Datasets
Total datasets for this author
Average FAIR Score
Average FAIR Score per dataset
Total Citations
Total citations to the author's datasets
Total Mentions
Total mentions of the author's datasets
S-Index Interpretation
The S-Index (Sharing Index) is a comprehensive metric that represents the cumulative impact of all your datasets. It is calculated as the sum of Dataset Index scores across all your claimed datasets.
What it means:
- A higher S-index indicates greater overall impact of your datasets relative to typical datasets in their fields of research
- The S-Index grows as you add more datasets or as existing datasets gain more citations and mentions
- It provides a single number to track your research data impact over time
Current S-Index: 0.6 (sum of 2 datasets Dataset Index scores)
More information here.
S-Index Over Time
Cumulative Citations Over Time
Cumulative Mentions Over Time
Datasets
This record contains raw data related to articleThis record contains raw data related to article "Macrophage expression and prognostic significance of the long pentraxin PTX3 in COVID-19" Abstract Long pentraxin 3 (PTX3) is an essential component of humoral innate immunity, involved in resistance to selected pathogens and in the regulation of inflammation1-3. The present study was designed to assess the presence and significance of PTX3 in Coronavirus Disease 2019 (COVID-19)4-7. RNA-sequencing analysis of peripheral blood mononuclear cells, single-cell bioinformatics analysis and immunohistochemistry of lung autopsy samples revealed that myelomonocytic cells and endothelial cells express high levels of PTX3 in patients with COVID-19. Increased plasma concentrations of PTX3 were detected in 96 patients with COVID-19. PTX3 emerged as a strong independent predictor of 28-d mortality in multivariable analysis, better than conventional markers of inflammation, in hospitalized patients with COVID-19. The prognostic significance of PTX3 abundance for mortality was confirmed in a second independent cohort (54 patients). Thus, circulating and lung myelomonocytic cells and endothelial cells are a major source of PTX3, and PTX3 plasma concentration can serve as an independent strong prognostic indicator of short-term mortality in COVID-19.
Authors
- Brunetta, Enrico ;
- Folci, Marco ;
- Bottazzi, Barbara ;
- Santis, Maria De ;
- Gritti, Giuseppe ;
- Protti, Alessandro ;
- Mapelli, Sarah N ;
- Bonovas, Stefanos ;
- Piovani, Daniele ;
- Leone, Roberto ;
- My, Ilaria ;
- Zanon, Veronica ;
- Spata, Gianmarco ;
- Bacci, Monica ;
- Supino, Domenico ;
- Carnevale, Silvia ;
- Sironi, Marina ;
- Davoudian, Sadaf ;
- Peano, Clelia ;
- Landi, Francesco ;
- Marco, Fabiano Di ;
- Raimondi, Federico ;
- Gianatti, Andrea ;
- Angelini, Claudio ;
- Rambaldi, Alessandro ;
- Garlanda, Cecilia ;
- Ciccarelli, Michele ;
- Cecconi, Maurizio ;
- Mantovani, Alberto
This record contains raw data related to articleThis record contains raw data related to article "Macrophage expression and prognostic significance of the long pentraxin PTX3 in COVID-19" Abstract Long pentraxin 3 (PTX3) is an essential component of humoral innate immunity, involved in resistance to selected pathogens and in the regulation of inflammation1-3. The present study was designed to assess the presence and significance of PTX3 in Coronavirus Disease 2019 (COVID-19)4-7. RNA-sequencing analysis of peripheral blood mononuclear cells, single-cell bioinformatics analysis and immunohistochemistry of lung autopsy samples revealed that myelomonocytic cells and endothelial cells express high levels of PTX3 in patients with COVID-19. Increased plasma concentrations of PTX3 were detected in 96 patients with COVID-19. PTX3 emerged as a strong independent predictor of 28-d mortality in multivariable analysis, better than conventional markers of inflammation, in hospitalized patients with COVID-19. The prognostic significance of PTX3 abundance for mortality was confirmed in a second independent cohort (54 patients). Thus, circulating and lung myelomonocytic cells and endothelial cells are a major source of PTX3, and PTX3 plasma concentration can serve as an independent strong prognostic indicator of short-term mortality in COVID-19.
Authors
- Brunetta, Enrico ;
- Folci, Marco ;
- Bottazzi, Barbara ;
- Santis, Maria De ;
- Gritti, Giuseppe ;
- Protti, Alessandro ;
- Mapelli, Sarah N ;
- Bonovas, Stefanos ;
- Piovani, Daniele ;
- Leone, Roberto ;
- My, Ilaria ;
- Zanon, Veronica ;
- Spata, Gianmarco ;
- Bacci, Monica ;
- Supino, Domenico ;
- Carnevale, Silvia ;
- Sironi, Marina ;
- Davoudian, Sadaf ;
- Peano, Clelia ;
- Landi, Francesco ;
- Marco, Fabiano Di ;
- Raimondi, Federico ;
- Gianatti, Andrea ;
- Angelini, Claudio ;
- Rambaldi, Alessandro ;
- Garlanda, Cecilia ;
- Ciccarelli, Michele ;
- Cecconi, Maurizio ;
- Mantovani, Alberto