Automated Author Profile

Ueda, Mitsuharu

Current S-Index

4.1

Sum of Dataset Indices for all datasets

Average Dataset Index per Dataset

0.5

Average Dataset Index per dataset

Total Datasets

9

Total datasets for this author

Average FAIR Score

28.8%

Average FAIR Score per dataset

Total Citations

3

Total citations to the author's datasets

Total Mentions

0

Total mentions of the author's datasets

S-Index Interpretation

S-Index Over Time

Cumulative Citations Over Time

Cumulative Mentions Over Time

Datasets

Hereditary transthyretin amyloidosis with cardiomyopathy and polyneuropathy associated with a novel pathogenic <i>TTR</i> Tyr105His (p.Tyr125His) mutation

Hereditary transthyretin amyloidosis with cardiomyopathy and polyneuropathy associated with a novel pathogenic TTR Tyr105His (p.Tyr125His) mutation

Authors

  • Nakamori, Masahiro ;
  • Tachiyama, Keisuke ;
  • Matsumura, Naoe ;
  • Hironaka, Akemi ;
  • Muraoka, Yuji ;
  • Kitagawa, Toshiro ;
  • Tasaki, Masayoshi ;
  • Yamakawa, Shiori ;
  • Ueda, Mitsuharu ;
  • Maruyama, Hirofumi
0 Citations0 Mentions13% FAIR0.1 Dataset Index
10.6084/m9.figshare.29839154January 2025

Hereditary transthyretin amyloidosis with cardiomyopathy and polyneuropathy associated with a novel pathogenic <i>TTR</i> Tyr105His (p.Tyr125His) mutation

Hereditary transthyretin amyloidosis with cardiomyopathy and polyneuropathy associated with a novel pathogenic TTR Tyr105His (p.Tyr125His) mutation

Authors

  • Nakamori, Masahiro ;
  • Tachiyama, Keisuke ;
  • Matsumura, Naoe ;
  • Hironaka, Akemi ;
  • Muraoka, Yuji ;
  • Kitagawa, Toshiro ;
  • Tasaki, Masayoshi ;
  • Yamakawa, Shiori ;
  • Ueda, Mitsuharu ;
  • Maruyama, Hirofumi
0 Citations0 Mentions13% FAIR0.1 Dataset Index
10.6084/m9.figshare.29839154.v1January 2025

High frequency of occult transthyretin and apolipoprotein AI–type amyloid in aortic valves removed by valve replacement for aortic stenosis

A high incidence of valvular involvement of amyloid in the setting of aortic stenosis (AS) has been reported. Amyloid derived from ApoAI (AApoAI) can form local amyloid deposits in the aortic valve. Although a high prevalence of concomitant severe AS and cardiac transthyretin-type amyloidosis (ATTR) has been reported, the prevalence of valvular involvement by ATTR and AApoAI is unclear. Using immunostaining and mass spectrometry, we analysed amyloid proteins in 97 aortic valves removed for valve replacement due to AS at Kyoto Prefectural University of Medicine between 2014 and 2021. Clinical information was also reviewed. Amyloid deposits were found in 44 cases (45%), of which 30 cases (68%) involved ATTR and 33 cases (75%) AApoAI. Statistical analysis showed significantly lower age and E/e′ among amyloid-positive cases compared with amyloid-negative cases and significantly lower brain natriuretic peptide, higher fractional shortening, and higher left ventricular ejection fraction among ATTR-positive cases compared with ATTR-negative cases. Seven recent patients underwent bone scintigraphy and ATTR cardiomyopathy was observed in only one case. AS symptoms can manifest earlier in patients with amyloid or ATTR deposition in the aortic valve than in patients without such deposition, even though left ventricular function is preserved.

Authors

  • Honda, Kohei ;
  • Tasaki, Masayoshi ;
  • Yamano, Tetsuhiro ;
  • Ueda, Mitsuharu ;
  • Naiki, Hironobu ;
  • Tanaka, Noriyuki ;
  • Morinaga, Yukiko ;
  • Miyagawa-Hayashino, Aya
1 Citation0 Mentions85% FAIR1.3 Dataset Index
10.6084/m9.figshare.27650876January 2024

High frequency of occult transthyretin and apolipoprotein AI–type amyloid in aortic valves removed by valve replacement for aortic stenosis

A high incidence of valvular involvement of amyloid in the setting of aortic stenosis (AS) has been reported. Amyloid derived from ApoAI (AApoAI) can form local amyloid deposits in the aortic valve. Although a high prevalence of concomitant severe AS and cardiac transthyretin-type amyloidosis (ATTR) has been reported, the prevalence of valvular involvement by ATTR and AApoAI is unclear. Using immunostaining and mass spectrometry, we analysed amyloid proteins in 97 aortic valves removed for valve replacement due to AS at Kyoto Prefectural University of Medicine between 2014 and 2021. Clinical information was also reviewed. Amyloid deposits were found in 44 cases (45%), of which 30 cases (68%) involved ATTR and 33 cases (75%) AApoAI. Statistical analysis showed significantly lower age and E/e′ among amyloid-positive cases compared with amyloid-negative cases and significantly lower brain natriuretic peptide, higher fractional shortening, and higher left ventricular ejection fraction among ATTR-positive cases compared with ATTR-negative cases. Seven recent patients underwent bone scintigraphy and ATTR cardiomyopathy was observed in only one case. AS symptoms can manifest earlier in patients with amyloid or ATTR deposition in the aortic valve than in patients without such deposition, even though left ventricular function is preserved.

Authors

  • Honda, Kohei ;
  • Tasaki, Masayoshi ;
  • Yamano, Tetsuhiro ;
  • Ueda, Mitsuharu ;
  • Naiki, Hironobu ;
  • Tanaka, Noriyuki ;
  • Morinaga, Yukiko ;
  • Miyagawa-Hayashino, Aya
1 Citation0 Mentions81% FAIR1.2 Dataset Index
10.6084/m9.figshare.27650876.v1January 2024

High frequency of occult transthyretin and apolipoprotein AI–type amyloid in aortic valves removed by valve replacement for aortic stenosis

A high incidence of valvular involvement of amyloid in the setting of aortic stenosis (AS) has been reported. Amyloid derived from ApoAI (AApoAI) can form local amyloid deposits in the aortic valve. Although a high prevalence of concomitant severe AS and cardiac transthyretin-type amyloidosis (ATTR) has been reported, the prevalence of valvular involvement by ATTR and AApoAI is unclear. Using immunostaining and mass spectrometry, we analysed amyloid proteins in 97 aortic valves removed for valve replacement due to AS at Kyoto Prefectural University of Medicine between 2014 and 2021. Clinical information was also reviewed. Amyloid deposits were found in 44 cases (45%), of which 30 cases (68%) involved ATTR and 33 cases (75%) AApoAI. Statistical analysis showed significantly lower age and E/e′ among amyloid-positive cases compared with amyloid-negative cases and significantly lower brain natriuretic peptide, higher fractional shortening, and higher left ventricular ejection fraction among ATTR-positive cases compared with ATTR-negative cases. Seven recent patients underwent bone scintigraphy and ATTR cardiomyopathy was observed in only one case. AS symptoms can manifest earlier in patients with amyloid or ATTR deposition in the aortic valve than in patients without such deposition, even though left ventricular function is preserved.

Authors

  • Honda, Kohei ;
  • Tasaki, Masayoshi ;
  • Yamano, Tetsuhiro ;
  • Ueda, Mitsuharu ;
  • Naiki, Hironobu ;
  • Tanaka, Noriyuki ;
  • Morinaga, Yukiko ;
  • Miyagawa-Hayashino, Aya
1 Citation0 Mentions13% FAIR0.5 Dataset Index
10.6084/m9.figshare.27650876.v2January 2024

Detection of semenogelin 1 amyloidosis through immunohistochemical staining with novel antiserum developed based on mass spectrometric peptide mapping analysis

Detection of semenogelin 1 amyloidosis through immunohistochemical staining with novel antiserum developed based on mass spectrometric peptide mapping analysis

Authors

  • Tasaki, Masayoshi ;
  • Misumi, Yohei ;
  • Nomura, Toshiya ;
  • Kamba, Tomomi ;
  • Ueda, Mitsuharu
0 Citations0 Mentions13% FAIR0.1 Dataset Index
10.6084/m9.figshare.21790189January 2022

Fibrinogen A α-chain amyloidosis associated with a rare frameshift pathogenic variant p.Arg547GlyfsTer21

Fibrinogen A α-chain amyloidosis associated with a rare frameshift pathogenic variant p.Arg547GlyfsTer21

Authors

  • Tasaki, Masayoshi ;
  • Nomura, Toshiya ;
  • Uchiyama, Koichi ;
  • Misumi, Yohei ;
  • Nakahara, Keiichi ;
  • Oyama, Yuzo ;
  • Uesugi, Noriko ;
  • Ueda, Mitsuharu
0 Citations0 Mentions13% FAIR0.3 Dataset Index
10.6084/m9.figshare.19745855.v1January 2022

Detection of semenogelin 1 amyloidosis through immunohistochemical staining with novel antiserum developed based on mass spectrometric peptide mapping analysis

Detection of semenogelin 1 amyloidosis through immunohistochemical staining with novel antiserum developed based on mass spectrometric peptide mapping analysis

Authors

  • Tasaki, Masayoshi ;
  • Misumi, Yohei ;
  • Nomura, Toshiya ;
  • Kamba, Tomomi ;
  • Ueda, Mitsuharu
0 Citations0 Mentions13% FAIR0.3 Dataset Index
10.6084/m9.figshare.21790189.v1January 2022

Fibrinogen A α-chain amyloidosis associated with a rare frameshift pathogenic variant p.Arg547GlyfsTer21

Fibrinogen A α-chain amyloidosis associated with a rare frameshift pathogenic variant p.Arg547GlyfsTer21

Authors

  • Tasaki, Masayoshi ;
  • Nomura, Toshiya ;
  • Uchiyama, Koichi ;
  • Misumi, Yohei ;
  • Nakahara, Keiichi ;
  • Oyama, Yuzo ;
  • Uesugi, Noriko ;
  • Ueda, Mitsuharu
0 Citations0 Mentions13% FAIR0.1 Dataset Index
10.6084/m9.figshare.19745855January 2022