Automated Author ProfileWanyi Huang
Wanyi Huang
Current S-Index
Sum of Dataset Indices for all datasets
Average Dataset Index per Dataset
Average Dataset Index per dataset
Total Datasets
Total datasets for this author
Average FAIR Score
Average FAIR Score per dataset
Total Citations
Total citations to the author's datasets
Total Mentions
Total mentions of the author's datasets
S-Index Interpretation
The S-Index (Sharing Index) is a comprehensive metric that represents the cumulative impact of all your datasets. It is calculated as the sum of Dataset Index scores across all your claimed datasets.
What it means:
- A higher S-index indicates greater overall impact of your datasets relative to typical datasets in their fields of research
- The S-Index grows as you add more datasets or as existing datasets gain more citations and mentions
- It provides a single number to track your research data impact over time
Current S-Index: 2.6 (sum of 2 datasets Dataset Index scores)
More information here.
S-Index Over Time
Cumulative Citations Over Time
Cumulative Mentions Over Time
Datasets
Abstract: Cryptosporidium hominis is a leading cause of severe diarrhea globally. In the United States, the incidence of cryptosporidiosis has increased substantially since 2005. Here we show the newly emerged IfA12G1R5 is now the dominant C. hominis subtype. In comparative analyses of 127 newly sequenced C. hominis genomes and 95 published ones, IfA12G1R5 isolates are placed in three of 14 clusters, indicating this subtype in the United States has multiple ancestral origins. Among the three variants, Pop6 has an East Africa origin and has gone through recombination with autochthonous subtypes after its arrival. In contrast, Pop13 is imported from Europe, where it has gone through recombination with the prevalent local subtype, while Pop14 is a progeny of secondary recombination between Pop6 and Pop13. Selective sweeps in invasion-associated genes have accompanied the emergence of the dominant Pop14 variant. These observations offer insights into the emergence and evolution of hyper-transmissible pathogens.
Authors
- Wanyi Huang
Abstract: Cryptosporidium hominis is a leading cause of severe diarrhea globally. In the United States, the incidence of cryptosporidiosis has increased substantially since 2005. Here we show the newly emerged IfA12G1R5 is now the dominant C. hominis subtype. In comparative analyses of 127 newly sequenced C. hominis genomes and 95 published ones, IfA12G1R5 isolates are placed in three of 14 clusters, indicating this subtype in the United States has multiple ancestral origins. Among the three variants, Pop6 has an East Africa origin and has gone through recombination with autochthonous subtypes after its arrival. In contrast, Pop13 is imported from Europe, where it has gone through recombination with the prevalent local subtype, while Pop14 is a progeny of secondary recombination between Pop6 and Pop13. Selective sweeps in invasion-associated genes have accompanied the emergence of the dominant Pop14 variant. These observations offer insights into the emergence and evolution of hyper-transmissible pathogens.
Authors
- Wanyi Huang