Automated Author Profile

Corral Lopez, Roberto

Universidad de Granada
0000-0002-5836-0071

Current S-Index

0.8

Sum of Dataset Indices for all datasets

Average Dataset Index per Dataset

0.8

Average Dataset Index per dataset

Total Datasets

1

Total datasets for this author

Average FAIR Score

69.2%

Average FAIR Score per dataset

Total Citations

1

Total citations to the author's datasets

Total Mentions

0

Total mentions of the author's datasets

S-Index Interpretation

S-Index Over Time

Cumulative Citations Over Time

Cumulative Mentions Over Time

Datasets

Soft trade-offs and the stochastic emergence of diversification in E. coli evolution experiments (Version: 7)

Laboratory experiments of bacterial colonies (e.g., Escherichia coli) under well-controlled conditions often lead to evolutionary diversification in which (at least) two ecotypes, each one specialized in the consumption of a different set of metabolic resources, branch out from an initially monomorphic population. Empirical evidence suggests that, even under fixed and stable conditions, such an "evolutionary branching'' occurs in a stochastic way, meaning that: (i) it is observed in a significant fraction, but not all, of the experimental repetitions, (ii) it may emerge at broadly diverse times, and (iii) the relative abundances of the resulting subpopulations are variable across experiments.  Theoretical approaches shedding light on the possible emergence of evolutionary branching in this type of condition have been previously developed within the theory of "adaptive dynamics''. Such approaches are typically deterministic –or incorporate at most demographic or finite-size fluctuations which become negligible for the extremely large populations of these experiments– and, thus, do not permit to reproduce the empirically observed large degree of variability. Here, we make further progress and shed new light on the stochastic nature of evolutionary outcomes by introducing the idea of "soft'' trade-offs (as opposed to"hard'' ones). This introduces a natural new source of stochasticity which allows one to account for the empirically observed variability as well as to make predictions for the possibility of evolutionary branching to be observed, thus helping to bridge the gap between theory and experiments.

Authors

  • Corral Lopez, Roberto ;
  • Suweis, Samir ;
  • Azaele, Sandro ;
  • Muñoz, Miguel
1 Citation0 Mentions69% FAIR0.8 Dataset Index
10.5061/dryad.3xsj3txn82023