Stress disorders became more prevalent in the modern era. Therefore, this must be addressed by employing natural and synthetic treatment approaches. Herbal therapies are the best preferred nutraceutical for treatment of stress disorders in current era. This approach may overcome few side effects like cardio toxicity, sexual dysfunction, sleep disorders etc. which is otherwise evident in synthetic drugs. Some herbal plants which are rich in flavonoids are studied for probable anti stress activity. Flavonoids are major source of antioxidants which helps in alleviation of neurological disorders which are characterized by production of free radicals and their destruction in CNS. These agents are experimented with the help of rodent animal models like rats and mice. The animals are induced with CUMS by exposing them to several stress stimuli. CUMS is a rodent paradigm which leads to oxidative stress and thereby neurological damage. After inducing CUMS, they are dosed with standard drug and test drug of different doses followed by assessment of behavioral and biochemical parameters.

Stress disorders became more prevalent in the modern era. Therefore, this must be addressed by employing natural and synthetic treatment approaches. Herbal therapies are the best preferred nutraceutical for treatment of stress disorders in current era. This approach may overcome few side effects like cardio toxicity, sexual dysfunction, sleep disorders etc. which is otherwise evident in synthetic drugs. Some herbal plants which are rich in flavonoids are studied for probable anti stress activity. Flavonoids are major source of antioxidants which helps in alleviation of neurological disorders which are characterized by production of free radicals and their destruction in CNS. These agents are experimented with the help of rodent animal models like rats and mice. The animals are induced with CUMS by exposing them to several stress stimuli. CUMS is a rodent paradigm which leads to oxidative stress and thereby neurological damage. After inducing CUMS, they are dosed with standard drug and test drug of different doses followed by assessment of behavioral and biochemical parameters.