Automated Author ProfileWang, Quan
The Eighth Affiliated Hospital, Xinjiang Medical University
Wang, Quan
Current S-Index
Sum of Dataset Indices for all datasets
Average Dataset Index per Dataset
Average Dataset Index per dataset
Total Datasets
Total datasets for this author
Average FAIR Score
Average FAIR Score per dataset
Total Citations
Total citations to the author's datasets
Total Mentions
Total mentions of the author's datasets
S-Index Interpretation
The S-Index (Sharing Index) is a comprehensive metric that represents the cumulative impact of all your datasets. It is calculated as the sum of Dataset Index scores across all your claimed datasets.
What it means:
- A higher S-index indicates greater overall impact of your datasets relative to typical datasets in their fields of research
- The S-Index grows as you add more datasets or as existing datasets gain more citations and mentions
- It provides a single number to track your research data impact over time
Current S-Index: 0.4 (sum of 1 dataset Dataset Index scores)
More information here.
S-Index Over Time
Cumulative Citations Over Time
Cumulative Mentions Over Time
Datasets
Objective This study investigated the variation and correlation of type 2 inherent lymphocytes (ILC2) and related factors in brucellosis, identified the immune role of ILC2 in the chronic brucellosis.Methods Forty-three patients with acute brucellosis and 45 patients with chronic brucellosis were compared with 49 healthy controls. The level of ILC2 in each group was detected by flow cytometry. The mRNA level of GATA3 in PBMC was detected by fluorescence quantitative PCR. The plasma levels of IL-33, ST2, IL-4 and IL-13 were detected by enzyme-linked immunosorbent assay (ELISA).Results The level of ILC2 cells in chronic brucellosis group was significantly higher than that in healthy control group and acute brucellosis group (P<0.01). The levels of GATA3 mRNA in PBMC, serum IL-33, IL-4 and IL-13 in chronic brucellosis group were significantly higher than those in healthy control group and acute brucellosis group (P<0.01). Correlation analysis showed that ILC2 cell level was positively correlated with GATA3 mRNA, IL-33, IL-4 and IL-13 levels, while ILC2 cell level was negatively correlated with ST2 levels. Conclusion The increase of ILC2 cells and its related factors is closely related to the chronic brucellosis, and may play an important role in the pathogenesis of brucellosis.
Authors
- Zhengwei Yin ;
- Yuejie Zhu ;
- Shi, Juan ;
- Yueyue He ;
- Jianbing Ding ;
- Wang, Quan ;
- Fengbo Zhang