Automated Author Profile

Gbaweng, Joël Abel

Current S-Index

1.3

Sum of Dataset Indices for all datasets

Average Dataset Index per Dataset

0.6

Average Dataset Index per dataset

Total Datasets

2

Total datasets for this author

Average FAIR Score

50.0%

Average FAIR Score per dataset

Total Citations

2

Total citations to the author's datasets

Total Mentions

0

Total mentions of the author's datasets

S-Index Interpretation

S-Index Over Time

Cumulative Citations Over Time

Cumulative Mentions Over Time

Datasets

Securidacaxanthone D: a new xanthone with free radical scavenging activity from the roots of <i>Securidaca longepedunculata</i> (Polygalaceae)

A previously unpublished xanthone named securidacaxanthone D (1) and five known analogues: 1,7-dihydroxyxanthone (2), 7-hydroxy-1,2-dimethoxy­xanthone (3), 1,5-dihydroxy-6,7-dimethoxyxanthone (4), 1,7-dihydroxy-3-methoxyxanthone (5), 1,7-dihydroxy-4-methxyxanthone (6) were isolated from the ethyl acetate soluble fraction obtained from the liquid-liquid partition of the crude hydro-ethanolic extract of the roots of Securidaca longipedunculata. Their structures were determined by analysis of 1D -(1H and 13C), 2D-(COSY, HSQC and HMBC) NMR data in conjunction with mass spectrometry (TOF-ESI-MS) and by comparison with reported data. Free radical scavenging activity were evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) as a free radical. Crude extract, ethyl acetate and n-butanol fractions as well as isolated compounds showed different degrees of free radical scavenging activity. Among the extract and fractions tested, the hydro-ethanolic extract was the most active with an IC50 value of 32 μg/mL. Among the compounds, compound 2 was the most active with an IC50 value of 282 μg/mL.

Authors

  • Tina, Janvier Hinmara ;
  • Tagousop, Cyrille Ngoufack ;
  • Abdouraman, Boubakary ;
  • Gbaweng, Joël Abel ;
  • Toko, Roméo Feunaing ;
  • Djouakoua, Judith Djithe ;
  • Morsia, Esther Lita ;
  • Henoumont, Céline ;
  • Laurent, Sophie ;
  • Talla, Emmanuel
1 Citation0 Mentions85% FAIR0.9 Dataset Index
10.6084/m9.figshare.287763762025

Securidacaxanthone D: a new xanthone with free radical scavenging activity from the roots of <i>Securidaca longepedunculata</i> (Polygalaceae)

A previously unpublished xanthone named securidacaxanthone D (1) and five known analogues: 1,7-dihydroxyxanthone (2), 7-hydroxy-1,2-dimethoxy­xanthone (3), 1,5-dihydroxy-6,7-dimethoxyxanthone (4), 1,7-dihydroxy-3-methoxyxanthone (5), 1,7-dihydroxy-4-methxyxanthone (6) were isolated from the ethyl acetate soluble fraction obtained from the liquid-liquid partition of the crude hydro-ethanolic extract of the roots of Securidaca longipedunculata. Their structures were determined by analysis of 1D -(1H and 13C), 2D-(COSY, HSQC and HMBC) NMR data in conjunction with mass spectrometry (TOF-ESI-MS) and by comparison with reported data. Free radical scavenging activity were evaluated using 1,1-diphenyl-2-picrylhydrazyl (DPPH) as a free radical. Crude extract, ethyl acetate and n-butanol fractions as well as isolated compounds showed different degrees of free radical scavenging activity. Among the extract and fractions tested, the hydro-ethanolic extract was the most active with an IC50 value of 32 μg/mL. Among the compounds, compound 2 was the most active with an IC50 value of 282 μg/mL.

Authors

  • Tina, Janvier Hinmara ;
  • Tagousop, Cyrille Ngoufack ;
  • Abdouraman, Boubakary ;
  • Gbaweng, Joël Abel ;
  • Toko, Roméo Feunaing ;
  • Djouakoua, Judith Djithe ;
  • Morsia, Esther Lita ;
  • Henoumont, Céline ;
  • Laurent, Sophie ;
  • Talla, Emmanuel
1 Citation0 Mentions15% FAIR0.4 Dataset Index
10.6084/m9.figshare.28776376.v12025