The files contain high-throuput sequencing read data from Novogene in FASTQ format, for all samples (0.1% EtOH treated vehicle control, 10nM PRI5202 treated, 315nM Fludarabine treated and combination treatment), in two out of six cell lines in the research article, published with the title: "Synergy in immunostimulatory and pro-differentiation effects of vitamin D analog and fludarabine in acute myeloid leukemias". The data from remaining 4 cell lines are uploaded in Zenodo separately, due to restriction of data size.The DOI for all other zenodo datasets are:1. 10.5281/zenodo.17609543 (Containing sequencing read data from wt-U937, U937-Empty cells, as well as reference genome data)2. 10.5281/zenodo.17610266 (Containing sequencing read data from U937-FGFR1 and U937-FGFR2 cells)The files are organised with titles according to the format: Cellline_Subline_Treatment_Read, where in:Cellline: HL for HL60, HE for HEL; Subline: WT for Wild type; Treatment: ETO for EtOH treated vehicle control, PRI for 10nM PRI5202, FLU for 315nM Fludarabine and CMB for combination of PRI5202 and Fludarabine (all treatments for 48 h); Read: 1 or 2, depending on direction of read strand.The data of genome-mapped raw read counts, and differentially expressed genes are available in a separate Zenodo dataset, accessible in DOI: 10.5281/zenodo.17610718

The files contain high-throuput sequencing read data from Novogene in FASTQ format, for all samples (0.1% EtOH treated vehicle control, 10nM PRI5202 treated, 315nM Fludarabine treated and combination treatment), in two out of six cell lines in the research article, published with the title: "Synergy in immunostimulatory and pro-differentiation effects of vitamin D analog and fludarabine in acute myeloid leukemias". The data from remaining 4 cell lines are uploaded in Zenodo separately, due to restriction of data size.The DOI for all other zenodo datasets are:1. 10.5281/zenodo.17609543 (Containing sequencing read data from wt-U937, U937-Empty cells, as well as reference genome data)2. 10.5281/zenodo.17610266 (Containing sequencing read data from U937-FGFR1 and U937-FGFR2 cells)The files are organised with titles according to the format: Cellline_Subline_Treatment_Read, where in:Cellline: HL for HL60, HE for HEL; Subline: WT for Wild type; Treatment: ETO for EtOH treated vehicle control, PRI for 10nM PRI5202, FLU for 315nM Fludarabine and CMB for combination of PRI5202 and Fludarabine (all treatments for 48 h); Read: 1 or 2, depending on direction of read strand.The data of genome-mapped raw read counts, and differentially expressed genes are available in a separate Zenodo dataset, accessible in DOI: 10.5281/zenodo.17610718

The files contain high-throuput sequencing read data from Novogene in FASTQ format, for all samples (0.1% EtOH treated vehicle control, 10nM PRI5202 treated, 315nM Fludarabine treated and combination treatment), in two out of six cell lines in the research article, published with the title: "Synergy in immunostimulatory and pro-differentiation effects of vitamin D analog and fludarabine in acute myeloid leukemias". The data from remaining 4 cell lines are uploaded in Zenodo separately, due to restriction of data size.The DOI for all other zenodo datasets are:1. 10.5281/zenodo.17609543 (Containing sequencing read data from wt-U937 and U937-Empty as well as reference genome data)2. 10.5281/zenodo.17610523 (Containing sequencing read data from HL60 and HEL cells)The files are organised with titles according to the format: Cellline_Subline_Treatment_Read, where in:Cellline: U for U937; Subline: F1 for FGFR1-overexpression plasmid transfected, F2 for FGFR2-overexpression plasmid transfected; Treatment: ETO for EtOH treated vehicle control, PRI for 10nM PRI5202, FLU for 315nM Fludarabine and CMB for combination of PRI5202 and Fludarabine (all treatments for 48 h); Read: 1 or 2, depending on direction of read strand.The data of genome-mapped raw read counts, and differentially expressed genes are available in a separate Zenodo dataset, accessible in DOI: 10.5281/zenodo.17610718

The files contain high-throuput sequencing read data from Novogene in FASTQ format, for all samples (0.1% EtOH treated vehicle control, 10nM PRI5202 treated, 315nM Fludarabine treated and combination treatment), in two out of six cell lines in the research article, published with the title: "Synergy in immunostimulatory and pro-differentiation effects of vitamin D analog and fludarabine in acute myeloid leukemias". The data from remaining 4 cell lines are uploaded in Zenodo separately, due to restriction of data size.The DOI for all other zenodo datasets are:1. 10.5281/zenodo.17609543 (Containing sequencing read data from wt-U937 and U937-Empty as well as reference genome data)2. 10.5281/zenodo.17610523 (Containing sequencing read data from HL60 and HEL cells)The files are organised with titles according to the format: Cellline_Subline_Treatment_Read, where in:Cellline: U for U937; Subline: F1 for FGFR1-overexpression plasmid transfected, F2 for FGFR2-overexpression plasmid transfected; Treatment: ETO for EtOH treated vehicle control, PRI for 10nM PRI5202, FLU for 315nM Fludarabine and CMB for combination of PRI5202 and Fludarabine (all treatments for 48 h); Read: 1 or 2, depending on direction of read strand.The data of genome-mapped raw read counts, and differentially expressed genes are available in a separate Zenodo dataset, accessible in DOI: 10.5281/zenodo.17610718

The files contain high-throuput sequencing read data from Novogene in FASTQ format, for all samples (0.1% EtOH treated vehicle control, 10nM PRI5202 treated, 315nM Fludarabine treated and combination treatment), in two out of six cell lines in the research article, published with the title: "Synergy in immunostimulatory and pro-differentiation effects of vitamin D analog and fludarabine in acute myeloid leukemias". The data from remaining 4 cell lines are uploaded in Zenodo separately, due to restriction of data size.The DOI for all other zenodo datasets are:1. 10.5281/zenodo.17610266 (Containing sequencing read data from U937-FGFR1 and U937-FGFR2 cells)2. 10.5281/zenodo.17610523 (Containing sequencing read data from HL60 and HEL cells)The files are organised with titles according to the format: Cellline_Subline_Treatment_Read, where in:Cellline: U for U937; Subline: WT for Wild type, EM for Empty; Treatment: ETO for EtOH treated vehicle control, PRI for 10nM PRI5202, FLU for 315nM Fludarabine and CMB for combination of PRI5202 and Fludarabine (all treatments for 48 h); Read: 1 or 2, depending on direction of read strand. In addition to the raw read files, this dataset contains the reference genome data used in this study, titled as "genome.fa", "genome.gtf" and "genome_gene.fa"The data of genome-mapped raw read counts, and differentially expressed genes are available in a separate Zenodo dataset, accessible in DOI: 10.5281/zenodo.17610718

The files contain high-throuput sequencing read data from Novogene in FASTQ format, for all samples (0.1% EtOH treated vehicle control, 10nM PRI5202 treated, 315nM Fludarabine treated and combination treatment), in two out of six cell lines in the research article, published with the title: "Synergy in immunostimulatory and pro-differentiation effects of vitamin D analog and fludarabine in acute myeloid leukemias". The data from remaining 4 cell lines are uploaded in Zenodo separately, due to restriction of data size.The DOI for all other zenodo datasets are:1. 10.5281/zenodo.17610266 (Containing sequencing read data from U937-FGFR1 and U937-FGFR2 cells)2. 10.5281/zenodo.17610523 (Containing sequencing read data from HL60 and HEL cells)The files are organised with titles according to the format: Cellline_Subline_Treatment_Read, where in:Cellline: U for U937; Subline: WT for Wild type, EM for Empty; Treatment: ETO for EtOH treated vehicle control, PRI for 10nM PRI5202, FLU for 315nM Fludarabine and CMB for combination of PRI5202 and Fludarabine (all treatments for 48 h); Read: 1 or 2, depending on direction of read strand. In addition to the raw read files, this dataset contains the reference genome data used in this study, titled as "genome.fa", "genome.gtf" and "genome_gene.fa"The data of genome-mapped raw read counts, and differentially expressed genes are available in a separate Zenodo dataset, accessible in DOI: 10.5281/zenodo.17610718