Automated Author Profile

Agcaoili, Ma. Joy Theresa

Mariano Marcos State University
0009-0002-4987-3075

Current S-Index

0.9

Sum of Dataset Indices for all datasets

Average Dataset Index per Dataset

0.5

Average Dataset Index per dataset

Total Datasets

2

Total datasets for this author

Average FAIR Score

92.3%

Average FAIR Score per dataset

Total Citations

0

Total citations to the author's datasets

Total Mentions

0

Total mentions of the author's datasets

S-Index Interpretation

S-Index Over Time

Cumulative Citations Over Time

Cumulative Mentions Over Time

Datasets

Heme Oxygenase 1 (HMOX1) Upregulation Accelerates Natural Immune Response in Black Garlic Cream Treated Mice

This study investigates garlic-based topical creams as anti-inflammatory treatments in a carrageenan-induced paw inflammation model in ICR mice. Phenotypic parameters (redness, temperature, volume) were recorded at 0, 2, 4, 6, and 8 hours post-treatment, and expression of IL-10, SOCS3, and HMOX1 alongside hematological indicators was assessed at 8 hours. Black garlic, fresh garlic, and mometasone furoate creams showed significant reductions in inflammation, with corticosteroid-treated mice exhibiting strong SOCS3 expression, while garlic treatments promoted HMOX1 upregulation and increased lymphocyte counts. The dataset supports the potential of black garlic as a natural anti-inflammatory agent via immune-regulatory pathways.

Authors

  • Vea, Rodge Carl ;
  • GANN, PETER JAMES ;
  • Agrupis, Shirley ;
  • Agcaoili, Ma. Joy Theresa ;
  • Fabia, Jimmbeth Zenila ;
  • Asuncion, Jessica
0 Citations0 Mentions92% FAIR0.5 Dataset Index
10.5281/zenodo.178235732025

Heme Oxygenase 1 (HMOX1) Upregulation Accelerates Natural Immune Response in Black Garlic Cream Treated Mice

This study investigates garlic-based topical creams as anti-inflammatory treatments in a carrageenan-induced paw inflammation model in ICR mice. Phenotypic parameters (redness, temperature, volume) were recorded at 0, 2, 4, 6, and 8 hours post-treatment, and expression of IL-10, SOCS3, and HMOX1 alongside hematological indicators was assessed at 8 hours. Black garlic, fresh garlic, and mometasone furoate creams showed significant reductions in inflammation, with corticosteroid-treated mice exhibiting strong SOCS3 expression, while garlic treatments promoted HMOX1 upregulation and increased lymphocyte counts. The dataset supports the potential of black garlic as a natural anti-inflammatory agent via immune-regulatory pathways.

Authors

  • Vea, Rodge Carl ;
  • GANN, PETER JAMES ;
  • Agrupis, Shirley ;
  • Agcaoili, Ma. Joy Theresa ;
  • Fabia, Jimmbeth Zenila ;
  • Asuncion, Jessica
0 Citations0 Mentions92% FAIR0.5 Dataset Index
10.5281/zenodo.178235722025