The Luc/RL ratios from dose-response experiments are presented in a tab-separated values file. Each row represents an experiment from a single well.Concentration. The molarity applied to the well. Note that the no-odor condition was coded as -12 in this column.NormLuc. The Luc/RL ratio from each well.OR. A unique ID for each olfactory receptor cloneOdor. A unique ID for the odorant applied to the wellDate. The date the experiment was run in MM/DD/YY format.

Each row represents a single odor. Further synonyms can be found in a file which correlates all of the CIDs in PubChem with submitted Synonyms (ftp://ftp.ncbi.nlm.nih.gov/pubchem/Compound/Extras/CID-Synonym-filtered.gz).Odor. A unique ID for the odorant, used in Data Records 1-3CASRegistryNum. The Chemical Abstracts Service number for the odorant, when available.OdorName. Common name for the odorant applied to the well.CID. PubChem Compound Identification number, a non-zero integer PubChem accession identifier for a unique chemical structure, when available.SMILES. Simplified Molecular-Input Line-Entry System string, an ASCII string identifier for a unique chemical structure.

The raw screening results are presented in a tab-separated values file. Each row represents an experiment from a single well. Plate. A unique ID for a 96-well plate on a given date. Well. A number assigned to each well of the 96-well plate. The wells are sequentially numbered with the upper-leftmost well assigned as 1 and the lower-leftmost well assigned as 85 (see Figure 3) Concentration. The concentration of the odorant applied in uM. A “9999” indicates no odor was applied (DMSO was diluted 1:10000 in CD293). Luc. The number of photons counted by the plate reader when the well was treated with the luciferase substrate. This is the cAMP reporter, and therefore correlates with receptor responses to odorants. RL. The number of photons counted by the plate reader when the well was treated with the Renilla luciferase substrate. This is the constitutively active reporter, which serves as a control for cell death and transfection efficiency. OR. A unique ID for each olfactory receptor clone Odor. A unique ID for the odorant applied to the well Date. The date the experiment was run in MM/DD/YY format.

Each row represents a single olfactory receptor.OR. A unique ID for the olfactory receptor, used in Data Records 1-3Gene. The gene name of the olfactory receptor encoded in a given plasmid, followed by the amino acid changes from the hg19 reference sequence for the gene. For example, “OR6Y1 V252I” encodes the gene OR6Y1, but while the hg19 reference sequence has a “V” as the 252nd amino acid, this clone encodes an “I” at position 252. Note that some plasmids were cloned from older builds of the genome, which may start at a different methionine than the current model. These differences from h19 reference may not appear here. Please consult the nucleotide sequence for a more thorough description of differences from the reference sequence.NucleotideSeq. The nucleotide sequence for the olfactory receptor encoded in a given plasmid. Note that the rhodopsin tag is not included in this field.

Each row represents an experiment from a single well.Date. The date the experiment was run in MM/DD/YY format.OR. A unique ID for each olfactory receptor cloneOdor. A unique ID for the odorant applied to the wellConcentration. The concentration of the odorant applied in uM. A “0” indicates no odor was applied (CD293 only). Note that rows for the “no odor” condition will contain an “Odor” label to facilitate pairing controls with the matched experiments at other concentrations.NormalizedLuc. The Luc/RL ratio from each well.Data Record 3 – Dose-ResponseThe Luc/RL ratios are presented in a tab-separated values file, deposited in figshare (http://dx.doi.org/10.6084/m9.figshare.979133). Each row represents an experiment from a single well.Concentration. The molarity applied to the well. Note that the no-odor condition was coded as -12 in this column.NormLuc. The Luc/RL ratio from each well.OR. A unique ID for each olfactory receptor cloneOdor. A unique ID for the odorant applied to the wellDate. The date the experiment was run in MM/DD/YY format.