Automated Author Profile
Yunhai Zhang

Current S-Index

9.6

Sum of Dataset Indices for all datasets

Average Dataset Index per Dataset

0.5

Average Dataset Index per dataset

Total Datasets

20

Total datasets for this author

Average FAIR Score

84.2%

Average FAIR Score per dataset

Total Citations

9

Total citations to the author's datasets

Total Mentions

0

Total mentions of the author's datasets

S-Index Interpretation

The S-Index (Sharing Index) is a comprehensive metric that represents the cumulative impact of all your datasets. It is calculated as the sum of Dataset Index scores across all your claimed datasets.

What it means:

A higher S-index indicates greater overall impact of your datasets relative to typical datasets in their fields of research
The S-Index grows as you add more datasets or as existing datasets gain more citations and mentions
It provides a single number to track your research data impact over time

Current S-Index: 9.6 (sum of 20 datasets Dataset Index scores)

More information here.

S-Index Over Time

Cumulative Citations Over Time

Cumulative Mentions Over Time

Datasets

Roles of Hedgehog signaling pathway in adipogenic differentiation potential of porcine adipose-derived mesenchymal stem cells

ABSTRACT This study examined the effects of purmorphamine and cyclopamine, classical agonists and inhibitors of the Hedgehog (Hh) signaling pathway, in the adipogenic differentiation of porcine adipose-derived mesenchymal stem cells (AMSC) to investigate the roles underlying adipogenic differentiation in AMSC. Porcine-derived AMSC were established, and the Hh signaling pathway was activated or inhibited by treatment with purmorphamine or cyclopamine. The adipogenic differentiation of the porcine AMSC was then analyzed by Oil Red O staining. The expression levels of Hh signaling pathway factors and adipogenic transcription factors were determined using quantitative real-time polymerase chain reaction and western blot analysis. We verified that the expression levels of positive regulators of the Hh pathway (Smo, Gli1, Gli2, and Gli3) decreased during adipogenesis, whereas those of negative regulators (Ptc1 and Ptc2) increased. Purmorphamine can inhibit the adipogenic differentiation of porcine AMSC in vitro culture. In addition, both the expression of the CCAAT/enhancerbindingprotein-α and that of the peroxisome proliferator-activated receptor-γ decreased in the presence of purmorphamine. By contrast, cyclopamine had no significant effect on the adipogenic differentiation of porcine AMSC. The Hh signaling pathway inhibits the adipogenic differentiation potential of porcine AMSC.

Authors

Caiyun Fan ;
Yunhai Zhang ;
Juhua Wang ;
Jianbo Cheng

0 Citations0 Mentions81% FAIR0.9 Dataset Index

10.6084/m9.figshare.74202352018

Roles of Hedgehog signaling pathway in adipogenic differentiation potential of porcine adipose-derived mesenchymal stem cells

ABSTRACT This study examined the effects of purmorphamine and cyclopamine, classical agonists and inhibitors of the Hedgehog (Hh) signaling pathway, in the adipogenic differentiation of porcine adipose-derived mesenchymal stem cells (AMSC) to investigate the roles underlying adipogenic differentiation in AMSC. Porcine-derived AMSC were established, and the Hh signaling pathway was activated or inhibited by treatment with purmorphamine or cyclopamine. The adipogenic differentiation of the porcine AMSC was then analyzed by Oil Red O staining. The expression levels of Hh signaling pathway factors and adipogenic transcription factors were determined using quantitative real-time polymerase chain reaction and western blot analysis. We verified that the expression levels of positive regulators of the Hh pathway (Smo, Gli1, Gli2, and Gli3) decreased during adipogenesis, whereas those of negative regulators (Ptc1 and Ptc2) increased. Purmorphamine can inhibit the adipogenic differentiation of porcine AMSC in vitro culture. In addition, both the expression of the CCAAT/enhancerbindingprotein-α and that of the peroxisome proliferator-activated receptor-γ decreased in the presence of purmorphamine. By contrast, cyclopamine had no significant effect on the adipogenic differentiation of porcine AMSC. The Hh signaling pathway inhibits the adipogenic differentiation potential of porcine AMSC.

Authors

Caiyun Fan ;
Yunhai Zhang ;
Juhua Wang ;
Jianbo Cheng

0 Citations0 Mentions81% FAIR1.8 Dataset Index

10.6084/m9.figshare.7420235.v12018

Additional file 5: of Screening and evaluating of long noncoding RNAs in the puberty of goats

GO analysis of predicted targets of lncRNAs in cis. (XLS 119Â kb)

Authors

Xiaoxiao Gao ;
Ye, Jing ;
Yang, Chen ;
Kaifa Zhang ;
Xiumei Li ;
Luo, Lei ;
Jianping Ding ;
Yunsheng Li ;
Hongguo Cao ;
Yinghui Ling ;
Xiaorong Zhang ;
Liu, Ya ;
Fugui Fang ;
Yunhai Zhang

0 Citations0 Mentions85% FAIR0.3 Dataset Index

10.6084/m9.figshare.c.3691690_d32017

Additional file 8: of Screening and evaluating of long noncoding RNAs in the puberty of goats

KEGG pathway analysis of predicted targets of lncRNAs in trans. (XLS 367Â kb)

Authors

Xiaoxiao Gao ;
Ye, Jing ;
Yang, Chen ;
Kaifa Zhang ;
Xiumei Li ;
Luo, Lei ;
Jianping Ding ;
Yunsheng Li ;
Hongguo Cao ;
Yinghui Ling ;
Xiaorong Zhang ;
Liu, Ya ;
Fugui Fang ;
Yunhai Zhang

0 Citations0 Mentions85% FAIR0.3 Dataset Index

10.6084/m9.figshare.c.3691690_d42017

Additional file 3: of Screening and evaluating of long noncoding RNAs in the puberty of goats

The protein-coding genes as potential targets 10K/100K upstream and downstream of the lncRNAs. (XLSX 372Â kb)

Authors

Xiaoxiao Gao ;
Ye, Jing ;
Yang, Chen ;
Kaifa Zhang ;
Xiumei Li ;
Luo, Lei ;
Jianping Ding ;
Yunsheng Li ;
Hongguo Cao ;
Yinghui Ling ;
Xiaorong Zhang ;
Liu, Ya ;
Fugui Fang ;
Yunhai Zhang

0 Citations0 Mentions85% FAIR0.3 Dataset Index

10.6084/m9.figshare.c.3691690_d52017

Additional file 9: of Screening and evaluating of long noncoding RNAs in the puberty of goats

The specific expression of lncRNAs in pubertal/prepubertal samples. (XLSX 36Â kb)

Authors

Xiaoxiao Gao ;
Ye, Jing ;
Yang, Chen ;
Kaifa Zhang ;
Xiumei Li ;
Luo, Lei ;
Jianping Ding ;
Yunsheng Li ;
Hongguo Cao ;
Yinghui Ling ;
Xiaorong Zhang ;
Liu, Ya ;
Fugui Fang ;
Yunhai Zhang

0 Citations0 Mentions85% FAIR0.3 Dataset Index

10.6084/m9.figshare.c.3691690_d62017

Additional file 4: of Screening and evaluating of long noncoding RNAs in the puberty of goats

The expression of protein-coding genes related puberty. (XLSX 10Â kb)

Authors

Xiaoxiao Gao ;
Ye, Jing ;
Yang, Chen ;
Kaifa Zhang ;
Xiumei Li ;
Luo, Lei ;
Jianping Ding ;
Yunsheng Li ;
Hongguo Cao ;
Yinghui Ling ;
Xiaorong Zhang ;
Liu, Ya ;
Fugui Fang ;
Yunhai Zhang

0 Citations0 Mentions85% FAIR0.3 Dataset Index

10.6084/m9.figshare.c.3691690_d72017

Additional file 1: of Screening and evaluating of long noncoding RNAs in the puberty of goats

The production of reads from the Illumina HiSeq 4000 platform. (XLSX 9Â kb)

Authors

Xiaoxiao Gao ;
Ye, Jing ;
Yang, Chen ;
Kaifa Zhang ;
Xiumei Li ;
Luo, Lei ;
Jianping Ding ;
Yunsheng Li ;
Hongguo Cao ;
Yinghui Ling ;
Xiaorong Zhang ;
Liu, Ya ;
Fugui Fang ;
Yunhai Zhang

0 Citations0 Mentions85% FAIR0.3 Dataset Index

10.6084/m9.figshare.c.3691690_d82017

Additional file 7: of Screening and evaluating of long noncoding RNAs in the puberty of goats

GO analysis of predicted targets of lncRNAs in trans. (XLS 1551Â kb)

Authors

Xiaoxiao Gao ;
Ye, Jing ;
Yang, Chen ;
Kaifa Zhang ;
Xiumei Li ;
Luo, Lei ;
Jianping Ding ;
Yunsheng Li ;
Hongguo Cao ;
Yinghui Ling ;
Xiaorong Zhang ;
Liu, Ya ;
Fugui Fang ;
Yunhai Zhang

0 Citations0 Mentions85% FAIR0.3 Dataset Index

10.6084/m9.figshare.c.3691690_d92017

Additional file 7: of Screening and evaluating of long noncoding RNAs in the puberty of goats

GO analysis of predicted targets of lncRNAs in trans. (XLS 1551Â kb)

Authors

Xiaoxiao Gao ;
Ye, Jing ;
Yang, Chen ;
Kaifa Zhang ;
Xiumei Li ;
Luo, Lei ;
Jianping Ding ;
Yunsheng Li ;
Hongguo Cao ;
Yinghui Ling ;
Xiaorong Zhang ;
Liu, Ya ;
Fugui Fang ;
Yunhai Zhang

1 Citation0 Mentions85% FAIR0.5 Dataset Index

10.6084/m9.figshare.c.3691690_d9.v12017