Automated Author ProfileNenutil, Rudolf
Nenutil, Rudolf
Current S-Index
Sum of Dataset Indices for all datasets
Average Dataset Index per Dataset
Average Dataset Index per dataset
Total Datasets
Total datasets for this author
Average FAIR Score
Average FAIR Score per dataset
Total Citations
Total citations to the author's datasets
Total Mentions
Total mentions of the author's datasets
S-Index Interpretation
The S-Index (Sharing Index) is a comprehensive metric that represents the cumulative impact of all your datasets. It is calculated as the sum of Dataset Index scores across all your claimed datasets.
What it means:
- A higher S-index indicates greater overall impact of your datasets relative to typical datasets in their fields of research
- The S-Index grows as you add more datasets or as existing datasets gain more citations and mentions
- It provides a single number to track your research data impact over time
Current S-Index: 7.3 (sum of 4 datasets Dataset Index scores)
More information here.
S-Index Over Time
Cumulative Citations Over Time
Cumulative Mentions Over Time
Datasets
Spreadsheet with data generated and analyzed during the study. (XLSX 20 kb)
Authors
- Bencsikova, Beatrix ;
- Budinska, Eva ;
- Selingerova, Iveta ;
- Pilatova, Katerina ;
- Fedorova, Lenka ;
- Greplova, Kristina ;
- Nenutil, Rudolf ;
- Valik, Dalibor ;
- Obermannova, Radka ;
- Sheard, Michael ;
- Zdrazilova-Dubska, Lenka
Spreadsheet with data generated and analyzed during the study. (XLSX 20 kb)
Authors
- Bencsikova, Beatrix ;
- Budinska, Eva ;
- Selingerova, Iveta ;
- Pilatova, Katerina ;
- Fedorova, Lenka ;
- Greplova, Kristina ;
- Nenutil, Rudolf ;
- Valik, Dalibor ;
- Obermannova, Radka ;
- Sheard, Michael ;
- Zdrazilova-Dubska, Lenka
Tamoxifen treatment in breast cancer patients is associated with increased risk of endometrial malignancies. Significantly, higher AGR2 expression was found in endometrial cancers that developed in women previously treated with tamoxifen compared to those who had not been exposed to tamoxifen. An association of elevated AGR2 level with myometrial invasion occurrence and invasion depth was also found. In vitro analyses identified a stimulatory effect of AGR2 on cellular proliferation. Although adverse tamoxifen effects on endometrial cells remain elusive, our work identifies elevated AGR2 as a candidate tamoxifen-dependent mechanism of action responsible for increased incidence of endometrial cancer.
Authors
- Hrstka, Roman ;
- Podhorec, Jan ;
- Nenutil, Rudolf ;
- Sommerova, Lucia ;
- Obacz, Joanna ;
- Durech, Michal ;
- Faktor, Jakub ;
- Bouchal, Pavel ;
- Skoupilova, Hana ;
- Vojtesek, Borivoj
Tamoxifen treatment in breast cancer patients is associated with increased risk of endometrial malignancies. Significantly, higher AGR2 expression was found in endometrial cancers that developed in women previously treated with tamoxifen compared to those who had not been exposed to tamoxifen. An association of elevated AGR2 level with myometrial invasion occurrence and invasion depth was also found. In vitro analyses identified a stimulatory effect of AGR2 on cellular proliferation. Although adverse tamoxifen effects on endometrial cells remain elusive, our work identifies elevated AGR2 as a candidate tamoxifen-dependent mechanism of action responsible for increased incidence of endometrial cancer.
Authors
- Hrstka, Roman ;
- Podhorec, Jan ;
- Nenutil, Rudolf ;
- Sommerova, Lucia ;
- Obacz, Joanna ;
- Durech, Michal ;
- Faktor, Jakub ;
- Bouchal, Pavel ;
- Skoupilova, Hana ;
- Vojtesek, Borivoj