Automated Author ProfileRajender, S.
Rajender, S.
Current S-Index
Sum of Dataset Indices for all datasets
Average Dataset Index per Dataset
Average Dataset Index per dataset
Total Datasets
Total datasets for this author
Average FAIR Score
Average FAIR Score per dataset
Total Citations
Total citations to the author's datasets
Total Mentions
Total mentions of the author's datasets
S-Index Interpretation
The S-Index (Sharing Index) is a comprehensive metric that represents the cumulative impact of all your datasets. It is calculated as the sum of Dataset Index scores across all your claimed datasets.
What it means:
- A higher S-index indicates greater overall impact of your datasets relative to typical datasets in their fields of research
- The S-Index grows as you add more datasets or as existing datasets gain more citations and mentions
- It provides a single number to track your research data impact over time
Current S-Index: 0.6 (sum of 2 datasets Dataset Index scores)
More information here.
S-Index Over Time
Cumulative Citations Over Time
Cumulative Mentions Over Time
Datasets
Background/Aims: This study aimed at investigating if M235T polymorphism in the AGT gene and A/GI8-83 polymorphism in the REN gene correlate with end-stage renal disease (ESRD). Methods: We analyzed 173 ESRD patients and 329 individuals with normal kidney function for differences in the genotype distribution of AGT-M235T and REN-A/GI8-83 polymorphisms between the two groups. The data for cases and controls were compared using the χ2 test. Results: We found significantly higher levels of serum creatinine and CRP in cases in comparison to controls (p < 0.0001). Data comparison showed a significant association of AGT M235T substitution with ESRD in the dominant model (p = 0.008) and in the comparison of the heterozygous substitution with the homozygous common genotype (p = 0.005). Similarly, REN A/GI8-83 polymorphism showed a significant difference in the distribution of genotypes between cases and controls (p < 0.038) such that a heterozygous substitution was significantly more common in the ESRD cases in comparison to the homozygous common genotype (p = 0.023). Conclusion: We conclude that heterozygous substitutions at the AGT M235T and REN A/GI8-83 loci correlate significantly with ESRD in a north Indian population.
Authors
- Sarkar, S. ;
- Gupta, V. ;
- Kumar, A. ;
- Chaudhary, M. ;
- Diyundi, S. ;
- Sehajpal, P.K. ;
- Thangaraj, K. ;
- Rajender, S.
Background/Aims: This study aimed at investigating if M235T polymorphism in the AGT gene and A/GI8-83 polymorphism in the REN gene correlate with end-stage renal disease (ESRD). Methods: We analyzed 173 ESRD patients and 329 individuals with normal kidney function for differences in the genotype distribution of AGT-M235T and REN-A/GI8-83 polymorphisms between the two groups. The data for cases and controls were compared using the χ2 test. Results: We found significantly higher levels of serum creatinine and CRP in cases in comparison to controls (p < 0.0001). Data comparison showed a significant association of AGT M235T substitution with ESRD in the dominant model (p = 0.008) and in the comparison of the heterozygous substitution with the homozygous common genotype (p = 0.005). Similarly, REN A/GI8-83 polymorphism showed a significant difference in the distribution of genotypes between cases and controls (p < 0.038) such that a heterozygous substitution was significantly more common in the ESRD cases in comparison to the homozygous common genotype (p = 0.023). Conclusion: We conclude that heterozygous substitutions at the AGT M235T and REN A/GI8-83 loci correlate significantly with ESRD in a north Indian population.
Authors
- Sarkar, S. ;
- Gupta, V. ;
- Kumar, A. ;
- Chaudhary, M. ;
- Diyundi, S. ;
- Sehajpal, P.K. ;
- Thangaraj, K. ;
- Rajender, S.