Automated Author Profile

Sun, Fangli

Northeast Forestry University

Current S-Index

2.2

Sum of Dataset Indices for all datasets

Average Dataset Index per Dataset

2.2

Average Dataset Index per dataset

Total Datasets

1

Total datasets for this author

Average FAIR Score

76.9%

Average FAIR Score per dataset

Total Citations

1

Total citations to the author's datasets

Total Mentions

0

Total mentions of the author's datasets

S-Index Interpretation

S-Index Over Time

Cumulative Citations Over Time

Cumulative Mentions Over Time

Datasets

Data from: Design of cinnamaldehyde amino acid Schiff base compounds based on the quantitative structure–activity relationship (Version: 1)

Cinnamaldehyde amino acid Schiff base (CAAS) is a new class of safe, bioactive compounds which could be developed as potential antifungal agents for fungal infections. To design new cinnamaldehyde amino acid Schiff base compounds with high bioactivity, the quantitative structure–activity relationships (QSARs) for CAAS compounds against Aspergillus niger (A. niger) and Penicillium citrinum (P. citrinum) were analysed. The QSAR models (R2 = 0.9346 for A. niger, R2 = 0.9590 for P. citrinum,) were constructed and validated. The models indicated that the molecular polarity and the Max atomic orbital electronic population had a significant effect on antifungal activity. Based on the best QSAR models, two new compounds were designed and synthesized. Antifungal activity tests proved that both of them have great bioactivity against the selected fungi.

Authors

  • Wang, Hui ;
  • Jiang, Mingyue ;
  • Li, Shujun ;
  • Hse, ChungYun ;
  • Jin, Chunde ;
  • Sun, Fangli ;
  • Li, Zhuo ;
  • Hse, Chung-Yun
1 Citation0 Mentions77% FAIR2.2 Dataset Index
10.5061/dryad.6pm502017