Automated Author ProfileChristiano, Romain
Christiano, Romain
Current S-Index
Sum of Dataset Indices for all datasets
Average Dataset Index per Dataset
Average Dataset Index per dataset
Total Datasets
Total datasets for this author
Average FAIR Score
Average FAIR Score per dataset
Total Citations
Total citations to the author's datasets
Total Mentions
Total mentions of the author's datasets
S-Index Interpretation
The S-Index (Sharing Index) is a comprehensive metric that represents the cumulative impact of all your datasets. It is calculated as the sum of Dataset Index scores across all your claimed datasets.
What it means:
- A higher S-index indicates greater overall impact of your datasets relative to typical datasets in their fields of research
- The S-Index grows as you add more datasets or as existing datasets gain more citations and mentions
- It provides a single number to track your research data impact over time
Current S-Index: 1.3 (sum of 2 datasets Dataset Index scores)
More information here.
S-Index Over Time
Cumulative Citations Over Time
Cumulative Mentions Over Time
Datasets
Golgin45 plays important roles in Golgi stack assembly and is known to bind both the Golgi stacking protein GRASP55 and Rab2 in the medial-Golgi cisternae. In this study, we sought to further characterize the cisternal adhesion complex using a proteomics approach. We report here that Acyl-CoA Binding Domain Containing 3 (ACBD3) is likely to be a novel binding partner of Golgin45. ACBD3 interacts with Golgin45 via its GOLD domain, and its co-expression significantly increases Golgin45 targeting to the Golgi. Further, ACBD3 recruits TBC1D22, a Rab33b GTPase Activating Protein (GAP), to a large multi-protein complex, containing Golgin45 and GRASP55. These results suggest that ACBD3 may provide a scaffolding to organize the Golgi stacking proteins and a Rab33b-GAP at the medial-Golgi.
Authors
- Xihua Yue ;
- Mengjing Bao ;
- Christiano, Romain ;
- Siyang Li ;
- Mei, Jia ;
- Lianhui Zhu ;
- Feifei Mao ;
- Yue, Qiang ;
- Panpan Zhang ;
- Shuaiyang Jing ;
- Rothman, James E ;
- Qian, Yi ;
- INTAEK LEE
Golgin45 plays important roles in Golgi stack assembly and is known to bind both the Golgi stacking protein GRASP55 and Rab2 in the medial-Golgi cisternae. In this study, we sought to further characterize the cisternal adhesion complex using a proteomics approach. We report here that Acyl-CoA Binding Domain Containing 3 (ACBD3) is likely to be a novel binding partner of Golgin45. ACBD3 interacts with Golgin45 via its GOLD domain, and its co-expression significantly increases Golgin45 targeting to the Golgi. Further, ACBD3 recruits TBC1D22, a Rab33b GTPase Activating Protein (GAP), to a large multi-protein complex, containing Golgin45 and GRASP55. These results suggest that ACBD3 may provide a scaffolding to organize the Golgi stacking proteins and a Rab33b-GAP at the medial-Golgi.
Authors
- Xihua Yue ;
- Mengjing Bao ;
- Christiano, Romain ;
- Siyang Li ;
- Mei, Jia ;
- Lianhui Zhu ;
- Feifei Mao ;
- Yue, Qiang ;
- Panpan Zhang ;
- Shuaiyang Jing ;
- Rothman, James E ;
- Qian, Yi ;
- INTAEK LEE