Paris Rive-Gauche BAG: from structure to drug design

Our BAG was created in 2006 to federate well-established structural biology laboratories from south Paris. At present, several projects are investigated by different teams from 5 Institutes: (1) I2BC (Institut de Biologie Intégrative de la Cellule), (2) IBPC (Institut de Biologie Physico-Chimique), (3) INSERM (Institut National de la Santé et de la Recherche Médicale), (4) LBPA (Laboratoire de Biologie et Pharmacologie Appliquée) and (5) CiTCoM (Cibles Thérapeutiques et Conception de Médicaments, ex-name LCRB). Our research area focuses on many important biological systems involved in human pathology or infectious diseases, including molecular chaperones, DNA recombination, RNA maturation, ribosome biogenesis, telomerase assembly, bacterial toxins, malaria disease, neurodegenerative disease, drugs resistance and cell-signalling.