Additional file 1 of Genome-wide analyses of multiple obesity-related cytokines and hormones informs biology of cardiometabolic traits

Additional file 1: Table S1: Number of samples per cohort and per obesity-related cytokine and hormone. Table S2: Total number of genome-wide significant (P-value < 5×10-8) loci detected in the discovery cohort, number of novel loci, and number of loci replicated in African Americans per trait and per model. Table S3: Variants at genome-wide significance of P-value < 5×10-8 with low MAF (<5%) before and after removal of high leverage points based on Cook's distance. Table S4: Variants at genome-wide significance of P-value < 5×10-8 per adipocytokine/hormone for the meta-analysis of discovery and replication cohorts combined. Table S5: Genome-wide significant loci from base model analyses with moderate or strong evidence for colocalization with eQTL data from GTEx. Table S6: Variants at genome-wide significance of P-value < 5×10-8 per adipocytokine/hormone for men only. Table S7: Variants at genome-wide significance of P-value < 5×10-8 per adipocytokine/hormone for women only. Table S8: Variants at genome-wide significance of P-value < 5×10-8 per adipocytokine/hormone for lean (BMI < 25.0 kg/m2) individuals only. Table S9: Variants at genome-wide significance of P-value < 5×10-8 per adipocytokine/hormone for overweight (BMI ≥ 25.0 kg/m2) individuals only. Table S10: Variants at genome-wide significance of P-value < 5×10-8 per adipocytokine/hormone for T2D controls only. Table S11: Variants at genome-wide significance of P-value < 5×10-8 per adipocytokine/hormone for T2D cases only. Table S12: Canonical pathways for genes annotated to genome-wide significant and suggestive loci in the base model