Greenness assessment of microextractiontechniques in therapeutic drug monitoring: supplementary materials

Aim: In this study, we evaluated the greenness and whiteness scores for microextraction techniques usedin therapeutic drug monitoring. Additionally, the cons and pros of each evaluated method and theirimpacts on the provided scores are also discussed. Materials & methods: The Analytical Greenness SamplePreparation metric tool and white analytical chemistry principles are used for related published works(2007–2023). Results & conclusion: This study provided valuable insights for developing methods basedon microextraction techniques with a balance in greenness and whiteness areas. Some methods basedon a specific technique recorded higher scores, making them suitable candidates as green analyticalapproaches, and some others achieved high scores both in green and white areas with a satisfactorybalance between principles.