dbCLINE Dataset

The dbCLINE dataset contains the results published inHancock AM, Witonsky DB, Alkorta-Aranburu G, Beall CM, Gebremedhin A, Sukernik R, Utermann G, Pritchard JK, Coop G, Di Rienzo A. Adaptations to climate-mediated selective pressures in humans. PLoS Genet. 2011. Hancock AM, Witonsky DB, Ehler E, Alkorta-Aranburu G, Beall C, Gebremedhin A, Sukernik R, Utermann G, Pritchard J, Coop G, Di Rienzo A. Colloquium paper: human adaptations to diet, subsistence, and ecoregion are due to subtle shifts in allele frequency. Proc Natl Acad Sci U S A. 2010 Applying the method of Coop et al. (2010) , the Di Rienzo lab conducted a genome-wide study to identify regions associated with variation in 20 environmental variables across 61 worldwide populations (52 HGDP + 9 in house genotyped on the Illumina 650Y platform;. These results had been formerly found in the online dbCLINE database at http://genapps.uchicago.edu/dbcline.See README.txt for additional information. NOTE: The allele frequencies contained in these data for the Amhara population is for an increased sample size of 60 individuals, not the 22 specified in Hancock et al. 2011.