Proteome-Wide Bioinformatic Annotation and Functional Validation of the Monotopic Phosphoglycosyl Transferase Superfamily

Durand, Theo;Dodge, Greg;Siuda, Roxanne;Higinbotham, Hugh;Arbour, Christine;Ghosh, Soumi;Allen, Karen;Imperiali, Barbara

Description

Optimized Sequence Similarity Networks (SSNs) of the SmPGT family allowing for functional annotation of clusters as validated in the published work. Datasets S1-S4 and S6 can all be visualized using Cytoscape. Dataset S1 is the network file for the E-value 1x 10-61, 100% representative node SmPGT network. Dataset S2 is the Cytoscape session file, with applied coloring, of the E-value 1x 10-61, 100% representative node SmPGT network. Dataset S3 is the network file for the E-value 1x 10-71, 100% representative node SmPGT network. Dataset S4 is the Cytoscape session file, with applied coloring, of the E-value 1x 10-61, 100% representative node SmPGT network. Dataset_5 is the Genome Neighbourhood Network of the E-71 SSN, viewable as diagrams on the EFI-EST server. Dataset_S6 is Genome Neighbourhood Diagrams of the clusters from the E-71 SSN, with the clusters as hub-nodes and neighbouring Pfam families as spoke-nodes

Citations (0)

Mentions (0)

Metrics

Dataset Index

0.4

FAIR Score

65%

Citations

0

Mentions

0

Metrics Over Time

Publication Details

DOI

Publisher

Mendeley Data

License

Creative Commons Attribution 4.0 International

Assigned Domain

Subfield

Molecular Biology

Field

Biochemistry, Genetics and Molecular Biology

Domain

Life Sciences

Confidence Score

54%

Source

Scholar Data Model

Keywords

Enzyme InhibitorGlycoconjugateMembrane ProteinBiosynthesis PathwayFunctional AnalysisGlycobiology

Normalization Factors

FT

53.85

CTw

1.00

MTw

1.00