Additional file 11 of PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands

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Mishra, Vasudha;Singh, Alka;Korzinkin, Michael;Cheng, Xiangying;Wing, Claudia;Sarkisova, Viktoria;Koppayi, Ashwin L.;Pogorelskaya, Alexandra;Glushchenko, Oksana;Sundaresan, Manu;Thodima, Venkat;Carter, Jack;Ito, Koichi;Scherle, Peggy;Trzcinska, Anna;Ozerov, Ivan;Vokes, Everett E.;Cole, Grayson;Pun, Frank W.;Shen, Le;Miao, Yuxuan;Pearson, Alexander T.;Lingen, Mark W.;Ruggeri, Bruce;Rosenberg, Ari J.;Zhavoronkov, Alex;Agrawal, Nishant;Izumchenko, Evgeny

Description

Supplementary Table 4: MSigDB Hallmark and KEGG pathways, sorted by the normalized enrichment score (NES), used in GSEA analysis of the transcriptomic data from ACC tumors and normal specimens. Top 25 upregulated pathways (labeled in red at the top of the list) and top 25 downregulated pathways (labeled in green at the bottom of the list) are depicted in Fig. 1B

Citations (0)

Mentions (0)

Metrics

Dataset Index

0.8

FAIR Score

85%

Citations

1

Mentions

0

Metrics Over Time

Publication Details

DOI

Publisher

figshare

License

Creative Commons Attribution 4.0 International

Assigned Domain

Subfield

Oncology

Field

Medicine

Domain

Health Sciences

Confidence Score

60%

Source

Scholar Data Model

Keywords

BiochemistryGeneticsFOS: Biological sciencesMolecular BiologyPharmacologyBiotechnologyChemical Sciences not elsewhere classifiedBiological Sciences not elsewhere classifiedInformation Systems not elsewhere classifiedCancer

Normalization Factors

FT

65.38

CTw

1.00

MTw

1.00