Single-cell ATAC sequencing data from: Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4-r cases
Thorsson, Hanna;Henningsson, Rasmus;Puente-Moncada, Noelia;Sjöström, Ludvig;Ågerstam, Helena;Peña-Martínez, Pablo;Sandén, Carl;Rissler, Marianne;Castor, Anders;Marquart, Hanne Vibeke;Modvig, Signe;Paulsson, Kajsa;Pronk, Cornelis Jan;Schmiegelow, Kjeld;Wittsten, Axel Hyrenius;Orsmark-Pietras, Christina;Lilljebjörn, Henrik;Fioretos, Thoas
Description
This dataset contains single-cell ATAC sequencing data from nineteen cases of childhood BCP-ALL and four samples of mononuclear cells from normal bone marrow from healthy donors. The dataset is available as raw sequencing reads (fastq; restricted access) or as an annotated ATAC dataset (h5ad). The libraries were prepared according to the manufacturer’s instructions (10x Genomics CG000169: Nuclei Isolation for Single Cell ATAC Sequencing; 10x Genomics CG000209: Chromium Single Cell ATAC Reagent Kits v1.1).) and sequenced on a Novaseq 6000.
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Publication Details
DOI
Publisher
Lund University
Subfield
Molecular Biology
Field
Biochemistry, Genetics and Molecular Biology
Domain
Life Sciences
Confidence Score
53%
Source
Scholar Data Model
Keywords
Cancer genetics