Dati medico_sanitari_completi(1).sav

Anticholinergic Burden in adult and elderly people with Intellectual Disabilities.The 2012 updated version of the Anticholinergic Burden Score (ACB) was calculated for a multicentre sample of 276 adult and older people over 40 years with ID
and associations with factors assessed. Antipsychotics, antiepileptics, anxiolytics, and antidepressants were
the most frequent classes contributing to the total ACB score. Residential care setting was associated with higher exposure (ACB score 3+), both community housing (OR 4.63, 95%CI 1.08 - 19.95) and nursing home facility (OR 9.99, 2.32 - 43.04) as were a mental health (OR 25.56, 95% CI 8.08 - 80.89) and a neurological (OR 4.14, 1.32 - 12.94) condition. Age and gender were not significant nor were the other clinical conditions (somatic comorbidity, level and typology of ID). Higher anticholinergic load was significantly more frequent in laxative users (22.6% ACB3+ vs. 5.1% ACB 0)
(p=0.003).