BindingDB Entry 50032319: Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: novel VEGFR2 kinase inhibitors binding to inactive kinase conformation.
BindingDB
Description
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Metrics Over Time
Publication Details
Subfield
Oncology
Field
Medicine
Domain
Health Sciences
Confidence Score
66%
Source
Scholar Data Model
Keywords
Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Fibroblast growth factor receptor 1, Focal adhesion kinase 1/vascular endothelial growth factor receptor 3, Glycogen synthase kinase-3, Insulin receptor, Insulin-like growth factor I receptor, Mitogen-activated protein kinase 3, Platelet-derived growth factor receptor, Platelet-derived growth factor receptor beta, Protein kinase C theta type, RAF serine/threonine protein kinase, Serine/threonine-protein kinase Aurora, Tyrosine-protein kinase Kit (Kit), VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Takeda Pharmaceutical Co., Ltd, Affinity