Additional file 6 of Comprehensive analysis of alternative splicing across multiple transcriptomic cohorts reveals prognostic signatures in prostate cancer

Mou, Zhuofan;Spencer, Jack;McGrath, John S.;Harries, Lorna W.

Description

Additional file 6: Table S6. Differentially expressed splicing factors and prognostic alternative splicing events. (a) Results of the differential gene expression analysis of the splicing factors in the TCCGA-PRAD dataset. TCGA: The Cancer Genome Atlas; PRAD: prostate adenocarcinoma; logFC: log2 transformed fold change; AveExpr: average expression (log2-transformed) for the gene over all samples; t: moderated t-statistic; P.Value: raw p-value; adj.P.Val:adjusted p-value using Benjamini-Hochberg (BH) approach; B: log-odds. (b) Results of the univariate Cox regression analysis of the biochemical recurrence-free survival (BCRFS)-associated events in the TCGA-PRAD datasets. TCGA: The Cancer Genome Atlas; PRAD: prostate adenocarcinoma; z: the values of the Wald statistic; HR: hazard ratio of the event; HR.95L: the lower limit of 95% confidence interval; HR.95H: the upper limit of the 95% confidence interval; p: p-values obtained from the likelihood ratio test.

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88%

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Publication Details

DOI

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figshare

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Creative Commons Attribution 4.0 International

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Molecular Biology

Field

Biochemistry, Genetics and Molecular Biology

Domain

Life Sciences

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56%

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Scholar Data Model

Keywords

BiochemistryMedicineCell BiologyGeneticsFOS: Biological sciencesMolecular BiologyBiological Sciences not elsewhere classifiedMathematical Sciences not elsewhere classifiedCancer

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1.00