Published on 01 January 2025
<b>Cambritaxestat</b><b> Reduces Tumor Growth</b> in mGC models
View DatasetCentonze, Matteo
Description
The study confirmed the efficacy of therapy targeting the ATX/LPA axis in advanced GC. Cambritaxestat, an ATX inhibitor with oral bioavailability and tolerability, is a promising candidate for combination with standard chemotherapy or antiangiogenic therapies, helping to overcome resistance and adapt conventional strategies.
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Keywords
Cancer therapy (excl. chemotherapy and radiation therapy)Cancer cell biologyMolecular targetsPredictive and prognostic markers