Functional noncoding variants within TBX1 enhancer contribute to Tetralogy of Fallot

This dataset contains single-cell RNA-sequencing (scRNA-seq) and chromatin immunoprecipitation sequencing (ChIP-seq) data generated from human embryonic stem cell (hESC)–derived vascular organoids. Vascular organoids were differentiated from wild-type (WT) and TBX1 enhancer-deleted hESC lines and collected at four developmental stages (Day 0, Day 5, Day 10, and Day 15) to model early human vascular lineage specification and maturation in vitro.