Version V1

Suilysin of Streptococcus suis serotype 2 drives astrocyte pyroptosis via activation of the ROS/NLRP3/caspase-1/GSDMD pathway

Ruicheng Yang;Tian, Lang;Jundan Wang;Wenquan Ouyang;Huanchun Chen;Xiangru Wang

Description

This dataset contains raw experimental data supporting the study "Suilysin of Streptococcus suis serotype 2 drives astrocyte pyroptosis via ROS/NLRP3/caspase-1/GSDMD pathway"—including SLY-induced pyroptosis metrics (LDH, IL-1β) in U251 cells (dose/time-dependent), ROS production data, in vivo astrocyte pyroptosis results (P1/7 vs P1/7-Δsly), and raw data for the article’s graphs/statistics (means, SDs). These data enable replication of the study’s key findings.

Citations (0)

Mentions (0)

Metrics

Dataset Index

0.4

FAIR Score

69%

Citations

0

Mentions

0

Metrics Over Time

Publication Details

DOI

Publisher

Science Data Bank

License

Creative Commons Attribution 4.0 International

Assigned Domain

Subfield

Parasitology

Field

Immunology and Microbiology

Domain

Life Sciences

Confidence Score

51%

Source

Scholar Data Model

Keywords

Veterinary medicineStreptococcus suis serotype 2suilysinastrocytespyroptosisNLRP3/caspase-1/GSDMD pathway

Normalization Factors

FT

65.38

CTw

1.00

MTw

1.00