Cell-type-specific GReX models trained on OneK1K by scTWAS

scTWAS_OneK1K_wgt.tar contains the significant cell-type-specific GReX weights (in FUSION format) on 13 immune cell types identified in our analysis. Only genes whose prediction p-values, evaluated under a cross-validation framework in Stage 1, passed the Bonferroni correction (< 0.05) are included.
These datasets contain weight files (formatted as *_scTWAS.wgt.RDat) generated via the scTWAS framework. Users should note the following specifications regarding the internal variables:wgt.matrix: Contains 10 columns representing 10 iterations of scTWAS. The last column was used as the final weight for all analyses. The SNP identifiers in wgt.matrix are formatted as chromosome:position, where the position corresponds to the GRCh37 genome build.Please disregard hsq and hsq.pv; these are not intended outputs of the scTWAS algorithm and should not be used for interpretation.