Additional file 1: of Pharmacological inhibition of ABCC3 slows tumour progression in animal models of pancreatic cancer
View DatasetAdamska, Aleksandra;Domenichini, Alice;Capone, Emily;Damiani, Verena;Akkaya, Begum;Linton, Kenneth;Sebastiano, Pierluigi;Chen, Xi;Keeton, Adam;Ramirez-Alcantara, Veronica;Maxuitenko, Yulia;Piazza, Gary;Laurenzi, Vincenzo;Sala, Gianluca;Falasca, Marco
Description
Figure S1. MCI-715- a specific inhibitor of ABCC3. Figure S2. Pharmacological inhibition of ABCC3 with MCI-715 reduces the activity of pSTAT3 Y705 and HIF1Îą. Figure S3. MCI-715 treatment in the animal models of PDAC. Figure S4. MCI-715 treatment induces apoptosis in the KPC primary cell line. Figure S5. Modulation of ABCC3 activity influences the viability of epithelial and stromal PDAC cells. (ZIP 4873 kb)
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Cited on 05 August 2019
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Publication Details
Subfield
Oncology
Field
Medicine
Domain
Health Sciences
Confidence Score
94%
Source
Open Alex
Keywords
BiochemistryMedicineCell BiologyMolecular BiologyNeurosciencePharmacologyBiotechnologyChemical Sciences not elsewhere classifiedDevelopmental BiologyCancerHematology