LDhat coalescent likelihood lookup table for 320 sequences with theta = 0.01
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The LDhat complete tool uses the method of Fearnhead and Donnelly (2001) to calculate coalescent likelihoods (via importance sampling) for all possible two-locus haplotype configurations for a given number of sequences for a grid of recombination rate (rho) values. See the LDhat documentation. We considered the case of 320 sequences, for which there are 708400 configurations. Generating this table was computationally expensive (approximately 60,000 CPU hours), hence the interest in sharing it for reuse. The included sbatch job script illustrates how the computations were done (with GNU Parallel). The script could be adapted to compute a similar table on Linux clusters that use Slurm for cluster management/job scheduling.
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Publication Details
DOI
Publisher
Zenodo
Subfield
Artificial Intelligence
Field
Computer Science
Domain
Physical Sciences
Confidence Score
99%
Source
Open Alex