Additional file 1 of Network analysis of the progranulin-deficient mouse brain proteome reveals pathogenic mechanisms shared in human frontotemporal dementia caused by GRN mutations

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Meixiang Huang;Modeste, Erica;Dammer, Eric;Merino, Paola;Taylor, Georgia;Duong, Duc M.;Qiudong Deng;Holler, Christopher J.;Gearing, Marla;Dickson, Dennis;Seyfried, Nicholas T.;Kukar, Thomas

Description

Additional file 1. Compilation of multiple supplementary tables. Table S1 is a list of cell type-specific protein markers used to identify enrichment of cell types in WGCNA modules. Table S3 is a summary of differential protein expression in Grn−/− (KO) compared to Grn+/+ (WT) mouse brain. Table s4 is a compilation of proteins identified in mouse brain proteome and their correlation to WGCNA modules. Table S5 is a summary of the enrichment of Gene Ontology (GO) terms for each module in WGCNA network.

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Metrics

Dataset Index

0.3

FAIR Score

85%

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0

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0

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Publication Details

DOI

Publisher

figshare

Assigned Domain

Subfield

Neurology

Field

Medicine

Domain

Health Sciences

Confidence Score

99%

Source

Open Alex

Keywords

BiochemistryMedicineCell BiologyGeneticsFOS: Biological sciencesMolecular BiologyNeurosciencePharmacology69999 Biological Sciences not elsewhere classified111714 Mental HealthFOS: Health sciences110309 Infectious DiseasesComputational Biology

Normalization Factors

FT

13.46

CTw

1.00

MTw

1.00