Version 5

The artificial-liver blood-purification system can effectively improve hypercytokinemia for COVID-19

Guo, Jing;Xia, He;Wang, Shuting;Yu, Liang;Zhang, Huafen;Chen, Jun;Shi, Ding;Chen, Yanfei;Zhang, Yan;Xu, Xiaowei;Xu, Kaijin;Sheng, Jifang;Qiu, Yunqing;Li, Lanjuan

Description

Since December 2019, the outbreak of Coronary Virus Disease 2019 (COVID-19) occurred in Wuhan, and rapidly spread across the country, and the world. As the number of diagnoses and deaths continues to rise, this has become the focus of international public health. COVID-19 is highly contagious, and there is no effective treatment. New treatment strategies are urgently needed to improve the treatment success rate of severe and critically ill patients. Increasing evidence has shown that cytokine storm plays an important role in the progression of COVID-19. The artificial liver blood purification system (ALS) is expected to improve the cytokine storm. In the present study, the levels of cytokines and chemokines were detected in 12 COVID-19 patients before and after ALS, and exciting results were obtained. The present study has directly proven that ALS can block the cytokine storm, rapidly remove the inflammatory mediators, and hopefully suppress the progression of the disease, providing a new idea for the clinical treatment of COVID-19.

Citations (0)

Mentions (0)

Metrics

Dataset Index

0.8

FAIR Score

69%

Citations

1

Mentions

0

Metrics Over Time

Publication Details

DOI

Publisher

Dryad

License

Creative Commons Zero v1.0 Universal

Assigned Domain

Subfield

Information Systems

Field

Computer Science

Domain

Physical Sciences

Confidence Score

56%

Source

Scholar Data Model

Normalization Factors

FT

51.92

CTw

1.00

MTw

1.00