Published on 01 January 2021
Additional file 1 of Intercellular transfer of exosomal wild type EGFR triggers osimertinib resistance in non-small cell lung cancer
View DatasetWu, Shaocong;Luo, Min;To, Kenneth K. W.;Zhang, Jianye;Su, Chaoyue;Zhang, Hong;An, Sainan;Wang, Fang;Chen, Da;Fu, Liwu
Description
Additional file 1: Figure S1. NSCLC cells harboring wtEGFR confer osimertinib resistance to sensitive mutEGFR cancer cells in vitro. Figure S2. Exosomal wtEGFR protein can be uptake by mutEGFR NSCLC cells via Clathrin. Figure S3. Osimertinib promotes the release of exosomes via RAB17. Table S1. shRNAs for RAB17, Caveolin-1, Clathrin and RAB27A. Table S2. Sequencing primers for EGFR mutation. Table S3. qPCR primers for screening and validation
Citations (1)
Cited on 18 January 2021
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Publication Details
Subfield
Pulmonary and Respiratory Medicine
Field
Medicine
Domain
Health Sciences
Confidence Score
85%
Source
Open Alex
Keywords
Space ScienceCell BiologyGeneticsFOS: Biological sciencesMolecular BiologyPharmacologyBiotechnologyBiological Sciences not elsewhere classifiedCancerHematologyPlant Biology