Aqueous glucose measured by NIR spectroscopy

Near infrared spectroscopy (NIR) is a promising technique that could be used for continuous blood glucose monitoring in the treatment of diabetic patients. Four interferents (lactate, ethanol, caffeine and acetaminophen) were introduced to study how the glucose predictions varied with interferent concentration. Lactate and ethanol was found to interfere with the glucose concentration when they were not included in the calibration of the model built with partial least squares regression modeling.