Description
A time lapse experiment of Saccharomyces cerevisiae expressing GFP tagged Cdc6. Cdc 6 is an essential ATP-binding protein required for DNA replication, component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p.These phase,gfp images are part of an image group that ranges from CIL:35660-35679. Note that there are additional groups showing time series of other cell cycle regulation proteins by the same authors in the Library.
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Metrics Over Time
Publication Details
Subfield
Molecular Biology
Field
Biochemistry, Genetics and Molecular Biology
Domain
Life Sciences
Confidence Score
57%
Source
Scholar Data Model
Keywords
Regulation of dna-dependent dna replication initiationChromatin bindingMannoprotein catabolic processSaccharomyces cerevisiaeATPase activityG1/S transition of mitotic cell cycleCDC6 proteinDomain: Biomedical and clinical sciencesGtpase activityPre-replicative complexRegulation of chromatin silencing at telomereProtein bindingATP bindingDNA replication origin bindingDNA replication preinitiation complexPre-replicative complex assemblyDomain: Biological sciences