Version 1
Data from: Mitochondrial capture by a transmissible cancer
View DatasetRebbeck, Clare A.;Leroi, Armand M.;Burt, Austin
Description
Canine transmissible venereal tumor (CTVT) is an infectious cell line circulating in many feral dog populations. It originated once, about 10,000 years ago. Phylogenetic analyses of mitochondrial sequences from dogs, wolves, and a geographically diverse collection of CTVT samples indicate that the cancer has periodically acquired mitochondria from its host. We suggest that this may be because the cancer’s own mitochondria have a tendency to degenerate, due to high mutation rates and relaxed selection, resulting in host mitochondria being more fit.
Citations (1)
- https://doi.org/10.1126/science.1197696DataCite MDC
Cited on 21 January 2011
Weight: 1.23
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Metrics Over Time
Publication Details
Subfield
Genetics
Field
Biochemistry, Genetics and Molecular Biology
Domain
Life Sciences
Confidence Score
47%
Source
Scholar Data Model
Keywords
Canis lupus familiarisCanis latransCanis lupusCanine transmissible cancer