RENEB/EURADOS field exercise 2019: robust dose estimation under outdoor conditions based on the dicentric chromosome assay

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Endesfelder, David;Oestreicher, Ursula;Kulka, Ulrike;Ainsbury, Elizabeth A.;Moquet, Jayne;Barnard, Stephen;Gregoire, Eric;Martinez, Juan S.;Trompier, François;Ristic, Yoann;Woda, Clemens;Waldner, Lovisa;Beinke, Christina;Vral, Anne;Barquinero, Joan-Francesc;Hernandez, Alfredo;Sommer, Sylwester;Lumniczky, Katalin;Hargitai, Rita;Montoro, Alegría;Milic, Mirta;Gil, Octávia Monteiro;Valente, Marco;Bobyk, Laure;Sevriukova, Olga;Sabatier, Laure;Prieto, María Jesús;Domene, Mercedes Moreno;Testa, Antonella;Patrono, Clarice;Terzoudi, Georgia;Triantopoulou, Sotiria;Histova, Rositsa;Wojcik, Andrzej

Description

Biological and/or physical assays for retrospective dosimetry are valuable tools to recover the exposure situation and to aid medical decision making. To further validate and improve such biological and physical assays, in 2019, EURADOS Working Group 10 and RENEB performed a field exercise in Lund, Sweden, to simulate various real-life exposure scenarios. For the dicentric chromosome assay (DCA), blood tubes were located at anthropomorphic phantoms positioned in different geometries and were irradiated with a 1.36 TBq 192Ir-source. For each exposure condition, dose estimates were provided by at least one laboratory and for four conditions by 17 participating RENEB laboratories. Three radio-photoluminescence glass dosimeters were placed at each tube to assess reference doses. The DCA results were homogeneous between participants and matched well with the reference doses (≥95% of estimates within ±0.5 Gy of the reference). For samples close to the source systematic underestimation could be corrected by accounting for exposure time. Heterogeneity within and between tubes was detected for reference doses as well as for DCA doses estimates. The participants were able to successfully estimate the doses and to provide important information on the exposure scenarios under conditions closely resembling a real-life situation.

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Metrics

Dataset Index

0.8

FAIR Score

85%

Citations

1

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0

Metrics Over Time

Publication Details

DOI

Publisher

Taylor & Francis

License

Creative Commons Attribution 4.0 International

Assigned Domain

Subfield

Complementary and alternative medicine

Field

Medicine

Domain

Health Sciences

Confidence Score

92%

Source

Open Alex

Keywords

MedicineBiotechnology59999 Environmental Sciences not elsewhere classifiedFOS: Earth and related environmental sciencesEcologyFOS: Biological sciences69999 Biological Sciences not elsewhere classifiedMarine BiologyScience Policy

Normalization Factors

FT

65.38

CTw

1.00

MTw

1.00