Automated Author Profile

Heneka, Michael

Current S-Index

2.6

Sum of Dataset Indices for all datasets

Average Dataset Index per Dataset

0.6

Average Dataset Index per dataset

Total Datasets

4

Total datasets for this author

Average FAIR Score

39.4%

Average FAIR Score per dataset

Total Citations

2

Total citations to the author's datasets

Total Mentions

0

Total mentions of the author's datasets

S-Index Interpretation

S-Index Over Time

Cumulative Citations Over Time

Cumulative Mentions Over Time

Datasets

Additional supplemental data Immunity paper: NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression

Secondary only controls for western blot(A) Microglia were primed with 100ng/ml LPS for 3 h, incubated with 1μM CRID3 or 100nM NP3-361 for 30 min and 5μM Aβ for 24 h. The lysates or (B) supernatants were prepared for immunoblot, and incubated with secondary only antibodies: goat anti-mouse 800 (used for NLRP3), goat anti-rabbit 680 (used for IL-1β) and goat anti-rat 680 (used for caspase-1). (C) The cortex of 4-, 6- and 12-month-old wild-type, APP/PS1, NLRP3-/- and APP/PS1.NLRP3-/- mice was prepared for immunoblot, and probed with secondary antibodies only. (D) Immunoblot analysis of secondary only controls from the cortex of patients with AD and non-demented, age-matched controls.

Authors

  • McManus, Róisín M. ;
  • Komes, Max P. ;
  • Griep, Angelika ;
  • Santarelli, Francesco ;
  • Schwartz, Stephanie ;
  • Perea, Juan Ramon ;
  • Schlachetzki, Johannes C.M. ;
  • Bouvier, David S. ;
  • Khalil, Michelle-Amirah ;
  • Lauterbach, Mario A. ;
  • Heinemann, Lea ;
  • Schlüter, Titus ;
  • Shaban Pour, Mehran ;
  • Lovotti, Marta ;
  • Stahl, Rainer ;
  • Duthie, Fraser ;
  • Rodríguez-Alcázar, Juan F. ;
  • Schmidt, Susanne V. ;
  • Spitzer, Jasper ;
  • Noori, Peri ;
  • Maillo, Alberto ;
  • Boettcher, Andreas ;
  • Herron, Brian ;
  • McConville, John ;
  • Gomez-Cabrero, David ;
  • tegner, jesper ;
  • Glass, Christopher K. ;
  • Hiller, Karsten ;
  • Latz, Eicke ;
  • Heneka, Michael
0 Citations0 Mentions65% FAIR0.7 Dataset Index
10.17632/m96m82x938January 2025

Additional supplemental data Immunity paper: NLRP3-mediated glutaminolysis controls microglial phagocytosis to promote Alzheimer’s disease progression

Secondary only controls for western blot(A) Microglia were primed with 100ng/ml LPS for 3 h, incubated with 1μM CRID3 or 100nM NP3-361 for 30 min and 5μM Aβ for 24 h. The lysates or (B) supernatants were prepared for immunoblot, and incubated with secondary only antibodies: goat anti-mouse 800 (used for NLRP3), goat anti-rabbit 680 (used for IL-1β) and goat anti-rat 680 (used for caspase-1). (C) The cortex of 4-, 6- and 12-month-old wild-type, APP/PS1, NLRP3-/- and APP/PS1.NLRP3-/- mice was prepared for immunoblot, and probed with secondary antibodies only. (D) Immunoblot analysis of secondary only controls from the cortex of patients with AD and non-demented, age-matched controls.

Authors

  • McManus, Róisín M. ;
  • Komes, Max P. ;
  • Griep, Angelika ;
  • Santarelli, Francesco ;
  • Schwartz, Stephanie ;
  • Perea, Juan Ramon ;
  • Schlachetzki, Johannes C.M. ;
  • Bouvier, David S. ;
  • Khalil, Michelle-Amirah ;
  • Lauterbach, Mario A. ;
  • Heinemann, Lea ;
  • Schlüter, Titus ;
  • Shaban Pour, Mehran ;
  • Lovotti, Marta ;
  • Stahl, Rainer ;
  • Duthie, Fraser ;
  • Rodríguez-Alcázar, Juan F. ;
  • Schmidt, Susanne V. ;
  • Spitzer, Jasper ;
  • Noori, Peri ;
  • Maillo, Alberto ;
  • Boettcher, Andreas ;
  • Herron, Brian ;
  • McConville, John ;
  • Gomez-Cabrero, David ;
  • tegner, jesper ;
  • Glass, Christopher K. ;
  • Hiller, Karsten ;
  • Latz, Eicke ;
  • Heneka, Michael
0 Citations0 Mentions65% FAIR0.7 Dataset Index
10.17632/m96m82x938.1January 2025

Additional file 1: of Transcriptome analysis of alcohol-treated microglia reveals downregulation of beta amyloid phagocytosis

Table S1. Differentially expressed mRNAs due to alcohol treatment “Alc-DEs”. Shading indicates mRNA levels were confirmed by qPCR. Table S2 Differentially expressed mRNAs due to TII treatment “TII-DEs”. Table S3 Differentially expressed mRNAs due to alcohol and TII treatment “AlcTII-DEs”. Table S4 Treatment-group overlap of differentially expressed mRNAs. Grey, involved in immune effector responses; Blue, mitochondrial ribosomal subunit; Orange, nuclear ribosomal subunit. Table S5 KEGG pathways identified in treatment groups. Table S6 FPKM (fragments per kilobase of transcript per million fragments mapped). (ZIP 3000 kb)

Authors

  • Kalinin, Sergey ;
  • González-Prieto, Marta ;
  • Scheiblich, Hannah ;
  • Lisi, Lucia ;
  • Handojo Kusumo ;
  • Heneka, Michael ;
  • Madrigal, Jose ;
  • Pandey, Subhash ;
  • Feinstein, Douglas
1 Citation0 Mentions13% FAIR0.7 Dataset Index
10.6084/m9.figshare.6268772January 2018

Additional file 1: of Transcriptome analysis of alcohol-treated microglia reveals downregulation of beta amyloid phagocytosis

Table S1. Differentially expressed mRNAs due to alcohol treatment “Alc-DEs”. Shading indicates mRNA levels were confirmed by qPCR. Table S2 Differentially expressed mRNAs due to TII treatment “TII-DEs”. Table S3 Differentially expressed mRNAs due to alcohol and TII treatment “AlcTII-DEs”. Table S4 Treatment-group overlap of differentially expressed mRNAs. Grey, involved in immune effector responses; Blue, mitochondrial ribosomal subunit; Orange, nuclear ribosomal subunit. Table S5 KEGG pathways identified in treatment groups. Table S6 FPKM (fragments per kilobase of transcript per million fragments mapped). (ZIP 3000 kb)

Authors

  • Kalinin, Sergey ;
  • González-Prieto, Marta ;
  • Scheiblich, Hannah ;
  • Lisi, Lucia ;
  • Handojo Kusumo ;
  • Heneka, Michael ;
  • Madrigal, Jose ;
  • Pandey, Subhash ;
  • Feinstein, Douglas
1 Citation0 Mentions13% FAIR0.5 Dataset Index
10.6084/m9.figshare.6268772.v1January 2018